Abstract Psychedelic drugs, including lysergic acid diethylamide and other agonists of the serotonin 2A receptor (5HT2A-R), induce drastic changes in subjective experience, and provide a unique opportunity to study the neurobiological basis of consciousness. One of the most notable neurophysiological signatures of psychedelics, increased entropy in spontaneous neural activity, is thought to be...
The scope of human consciousness includes states departing from what most of\nus experience as ordinary wakefulness. These altered states of consciousness\nconstitute a prime opportunity to study how global changes in brain activity\nrelate to different varieties of subjective experience. We consider the problem\nof explaining how global signatures of altered consciousness arise from...
The scope of human consciousness includes states departing from what most of us experience as ordinary wakefulness. These altered states of consciousness constitute a prime opportunity to study how global changes in brain activity relate to different varieties of subjective experience. We consider the problem of explaining how global signatures of altered consciousness arise from the interplay...
Abstract Quantifying the complexity of neural activity has provided fundamental insights into cognition, consciousness, and clinical conditions. However, the most widely used approach to estimate the complexity of neural dynamics, Lempel-Ziv complexity (LZ), has fundamental limitations that substantially restrict its domain of applicability. In this article we leverage the information-theoretic...
The relationship between subjectivity and its substrate can be understood via the notion of compatibilist emergence, accounting for the plurality of ways nature can host new dynamical laws at higher scales. We discuss how the autopoietic character of life may require and promote the kind of emergence necessary, albeit not sufficient, for consciousness.