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Liang Wang

3 papers in the library · 145 citations · publishing 2017-2025

Papers

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The Construction Approach of Machine Consciousness and Its Limitations

Computer Sciences & Mathematics Forum March 26, 2025 Liang Wang, Ziyi Ma

Along with the development of artificial-intelligence technology, the construction of machine consciousness has become a hot issue studied by scholars. Generally speaking, the research methods of machine consciousness are mainly divided into two approaches: the algorithm-construction strategy and the brain-like-construction strategy. The algorithm-construction strategy refers to the research of...

DOI: 10.3390/cmsf2023008016 (opens in new tab) Full text (opens in new tab) Machine consciousness Construction approach Limitations

AlphaFold2 structures guide prospective ligand discovery

Science May 16, 2024 Jiankun Lyu, Nicholas J. Kapolka, Ryan H. Gumpper et al. 145 citations

AlphaFold2 (AF2) models have had wide impact but mixed success in retrospective ligand recognition. We prospectively docked large libraries against unrefined AF2 models of the σ 2 and serotonin 2A (5-HT2A) receptors, testing hundreds of new molecules and comparing results with those obtained from docking against the experimental structures. Hit rates were high and similar for the experimental...

DOI: 10.1126/science.adn6354 (opens in new tab) Full text (opens in new tab) Docking animal Computational biology Affinities Stereochemistry +5

Meditation and blood pressure: a meta-analysis of randomized clinical trials.

Journal of Hypertension April 2017 Lu Shi, Donglan Zhang, Liang Wang et al.

We meta-analyzed the effect of meditation on blood pressure (BP), including both transcendental meditation and non-transcendental meditation interventions. We identified randomized controlled trials (RCTs) that examined the BP responses to meditation interventions through a systematic literature search of the PubMed, ABI/INFORM, MEDLINE, EMBASE, PsycINFO, and CINAHL databases (from January 1980...