3 papers in the library · 51 citations · publishing 2017-2026
Journal of Contextual Behavioral Science October 1, 2019 Jason B. Luoma, Pablo Sabucedo, Johan Eriksson et al. 51 citations
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Scientific Reports March 10, 2026 Olympia Karampela, Aurelie Fontan, Lenita Lindgren et al.
Noradrenergic activity plays a key role in conscious visuospatial processing, distinct from general arousal effects. Two experiments—one using the sedative Dexmedetomidine (which targets α2A noradrenergic receptors) and another using sleep deprivation—both selectively altered brain activity (fMRI BOLD signal) during conscious processing, unlike the sedative Propofol, which affects both conscious and unconscious processing. However, the two methods produced opposite effects on visuospatial bias: Dexmedetomidine reduced leftward bias, while sleep deprivation increased leftward bias. The sleep deprivation effect was linked to an unexpected increase in sympathetic drive, indicated by heightened central autonomic network activity and heart rate, suggesting increased noradrenaline levels during task performance. These findings highlight noradrenergic activity as a target for studying consciousness.
Consciousness and Cognition October 1, 2017 Johan Eriksson
Integration is often considered essential for generating conscious experiences, so brain activity linked to consciousness should increase when integration demands rise. Using fMRI and informational masking, researchers compared hearing simple repeating tones versus harmonic tone triplets to manipulate integration. The neural correlates of auditory consciousness included the superior temporal gyrus, lateral and medial frontal regions, cerebellum, and parietal cortex. Only left parietal cortex activity increased significantly with greater integration demands. Integration accounts for part of the neural activity underlying conscious experiences, but much of the associated brain activity likely reflects other processes.