The behavioral and neurochemical effects of phencyclidine in humans and animals: some implications for modeling psychosis.
Behavioural Brain Research 1996 R E Steinpreis
Phencyclidine (PCP) produces a psychotic reaction in humans which closely resembles an acute episode of schizophrenia and has therefore been given an increasing amount of attention as a model for schizophrenia. The present article reviews the behavioral and neurochemical effects of PCP in both humans and animals. Where possible, comparisons are made between the effects of PCP and amphetamine....