bioRxiv (Cold Spring Harbor Laboratory)
January 2, 2026
Jason C. Slot, Alexander J. Bradshaw, Bryn T. M. Dentinger et al.
Abstract Production of the psychoactive compound psilocybin is a defining feature of the genus Psilocybe , commonly referred to as “psychedelic mushrooms”. However, Psilocybe fuscofulva is a striking exception within Psilocybe sensu stricto as it lacks the stereotypical blue bruising characteristic of the genus, and psilocybin has not been detected in the species.To investigate the evolutionary...
The International Journal of Neuropsychopharmacology
February 1, 2025
Martin Kuchař, Klara Gotwaldova, Jan Borovička et al.
1 citation
Abstract Synthetic psilocybin (PSB), but also the PSB-containing mushrooms are used for psychedelic therapy and microdosing. It is necessary to know alkaloids variability and stability in wild-grown mushrooms. Concentrations of other psychotropic (or potentially psychotropic) tryptamines such as psilocin (PS), baeocystin (BA), norbaeocystin (NB), and aeruginascin (AE) are also relevant. This...
International Journal of Molecular Sciences
November 15, 2022
Klára Gotvaldová, Jan Borovička, Kateřina Hájková et al.
50 citations
Since not only psilocybin (PSB) but also PSB-containing mushrooms are used for psychedelic therapy and microdosing, it is necessary to know their concentration variability in wild-grown mushrooms. This article aimed to determine the PSB, psilocin (PS), baeocystin (BA), norbaeocystin (NB), and aeruginascin (AE) concentrations in a large sample set of mushrooms belonging to genera previously...
Drug Testing and Analysis
October 29, 2020
Klára Gotvaldová, Kateřina Hájková, Jan Borovička et al.
69 citations
Abstract Psilocybin, psilocin, baeocystin, norbaeocystin, and aeruginascin are tryptamines structurally similar to the neurotransmitter serotonin. Psilocybin and its pharmacologically active metabolite psilocin in particular are known for their psychoactive effects. These substances typically occur in most species of the genus Psilocybe (Fungi, Strophariaceae). Even the sclerotia of some of...
Persoonia - Molecular Phylogeny and Evolution of Fungi
November 26, 2014
Jan Borovička, Miroslav Obornı́k, J Strĭbrný et al.
30 citations
Five Psilocybe species with unresolved systematic position ( P. atrobrunnea , P. laetissima , P. medul- losa , P. pelliculosa , and P. silvatica ) were investigated using four molecular markers (EF1-α, ITS, LSU, and IGS). Phylogenetic analysis revealed that with the exception of P. laetissima , which is now rightfully classified in the genus Leratiomyces , all investigated species belong to...