Geraldo F. Busatto

2 papers in the library · 207 citations · publishing 2009-2018

Papers

Neuroimaging in cannabis use: a systematic review of the literature

Psychological Medicine July 23, 2009 R. Martín-Santos, Ana B. Fagundo, José Alexandre S. Crippa et al. 207 citations

A systematic review of neuroimaging studies published up to January 2009 assessed evidence for cannabis effects on brain structure and function. Among 41 included studies, functional imaging indicated that resting global and prefrontal blood flow are lower in cannabis users than in controls. Activation studies during cognitive tasks produced inconsistent results. Acute administration of THC or marijuana increased resting activity and activation of the frontal and anterior cingulate cortex during cognitive tasks. Only three of eight structural imaging studies found differences between users and controls, providing minimal evidence of major effects of cannabis on brain structure.

DOI: 10.1017/s0033291709990729 Cannabidiol Positron emission tomography Medicine Resting State FMRI +11

Aerobic training modulates salience network and default mode network metabolism in subjects with mild cognitive impairment

NeuroImage: Clinical August 22, 2018 F.H.G. Porto, Artur Martins Coutinho, Fabio Luís de Souza Duran et al.

A 24-week moderate-intensity aerobic training program in 65 people with mild cognitive impairment altered resting brain glucose metabolism in key networks. Metabolism decreased in the salience network (anterior temporal lobes, anterior cingulate, hippocampus, caudate) and increased in the default mode network (precuneus). These changes moved toward the metabolic patterns expected in healthy aging, suggesting improved efficiency of the salience network and greater control over other brain networks.

DOI: 10.1016/j.nicl.2018.05.002 Full text