Experimental and Clinical Psychopharmacology
August 1, 2016
Albert Garcia‐romeu, Brennan Kersgaard, Peter H. Addy
198 citations
Hallucinogens fall into several different classes, as broadly defined by pharmacological mechanism of action, and chemical structure. These include psychedelics, entactogens, dissociatives, and other atypical hallucinogens. Although these classes do not share a common primary mechanism of action, they do exhibit important similarities in their ability to occasion temporary but profound...
The Lancet Psychiatry
April 5, 2016
Michael C Mithoefer, Charles S. Grob, Timothy D Brewerton
237 citations
4-phosphorloxy-N,N-dimethyltryptamine (psilocybin) and methylenedioxymethamfetamine (MDMA), best known for their illegal use as psychedelic drugs, are showing promise as therapeutics in a resurgence of clinical research during the past 10 years. Psilocybin is being tested for alcoholism, smoking cessation, and in patients with advanced cancer with anxiety. MDMA is showing encouraging results as...
European Journal of Psychotraumatology
November 19, 2015
Tobias Hecker, Lars Braitmayer, Marjolein Van Duijl
50 citations
Background: We present a literature review on trauma exposure and spirit possession in low- and middle-income countries (LMICs). Despite the World Health Organization's objective of culturally appropriate mental health care in the Mental Health Action Plan 2013-2020, and the recommendations of the Inter-Agency Standing Committee to consider local idioms of distress and to collaborate with local...
Australasian Psychiatry
June 2015
Deborah Wearne, Amanda Genetti
This paper firstly explores the historical concept of pseudohallucinations and their phenomenology. It then examines the experience of hallucinosis in two subject groups, one with post-traumatic stress disorder with dissociative symptoms and the second with schizophrenia. The two groups were assessed using the Psychotic Symptoms Rating Scale with a view to identifying differences in the...
Frontiers in Human Neuroscience
2015
Peter Payne, Mardi A Crane-Godreau
Basic to all motile life is a differential approach/avoid response to perceived features of environment. The stages of response are initial reflexive noticing and orienting to the stimulus, preparation, and execution of response. Preparation involves a coordination of many aspects of the organism: muscle tone, posture, breathing, autonomic functions, motivational/emotional state, attentional...
Human Psychopharmacology: Clinical and Experimental
March 2014
Andrew C. Parrott
Human Psychopharmacology recently published my review into the increase in empirical knowledge about the human psychobiology of MDMA over the past 25 years (Parrott, 2013a). Deficits have been demonstrated in retrospective memory, prospective memory, higher cognition, complex visual processing, sleep architecture, sleep apnoea, pain, neurohormonal activity, and psychiatric status. Neuroimaging...
World neurosurgery
2013
R Aaron Robison, Alexander Taghva, Charles Y. Liu et al.
Since the beginning of recorded history, humans have sought a physical means of altering disordered behavior and consciousness. This quest has spawned numerous innovations in neurosurgery and the neurosciences, from the earliest prehistoric attempts at trepanation to the electrocortical and anatomic localization of cerebral function that emerged in the 19th century. At the start of the 20th...
heiDOK (Heidelberg University)
2009
Valérie Schäfer, Klaus Bader
6 citations
Summary. There is ample evidence that bad dreams and post-traumatic nightmares are a common consequence of exposure to traumatic events both among children and adults. The aim of the present study was to examine to what extent early-life maltreatment experiences are associated with dreams even many years later in adulthood. 37 patients suffering from primary insomnia recorded their dreams for...
Frontiers in Psychology
October 27, 2026
Nasiru Mohammed Abdullahi, Rashid Menhas, Patience Osose Nasir et al.
Background: Clinical research on psychedelic-assisted therapy (PAT) has expanded substantially in recent years, particularly for post-traumatic stress disorder (PTSD) and depressive disorders. Contemporary studies have generally evaluated psychedelic administration within controlled therapeutic settings that include psychological support, preparation, and integration. However, variability in...
Zenodo (CERN European Organization for Nuclear Research)
October 24, 2026
Juan Camilo Vargas-Nieto, Vanesa Castro-Sanabria, Mateo Bernal et al.
preprint
Populations in Low- and Middle-Income Countries (LMICs) bear a disproportionate burden of mental health conditions, including anxiety, depression, and post-traumatic stress disorder (PTSD), often exacerbated by conflict, poverty, and limited healthcare infrastructure. The gap between the need for and the availability of mental health services is particularly wide in these settings. Third-wave...