Psychedelic-assisted therapy: all studies (page 4)

Ketamine assisted psychotherapy to reduce chronic neuropathic pain: A mixed-methods randomized pilot trial.

Med August 13, 2026

Ketamine assisted psychotherapy to reduce chronic neuropathic pain: A mixed-methods randomized pilot trial.

DOI: 10.1016/j.medj.2026.101259

How is caregiver involvement conceptualized across oncology, palliative care, and psychedelic-assisted therapy literature, and which relational mechanisms can inform its use in oncology-based psychedelic care?

Zenodo (CERN European Organization for Nuclear Research) August 12, 2026 preprint

Current evidence highlights the importance of caregiver involvement in oncology and palliative care, emphasizing communication and decision-making. No direct evidence exists for psychedelic-assisted therapy in oncology, highlighting a need for research exploring caregiver roles in this context.

DOI: 10.5281/zenodo.21906477

Psychedelic Therapy for Depression

Zenodo (CERN European Organization for Nuclear Research) August 11, 2026 Saanvi Gutta preprint

Depression affects over 280 million people worldwide and remains one of the leading causes of disability and suicide. Existing treatments such as SSRIs and traditional psychotherapy often fail to provide relief, especially for individuals with treatment‑resistant depression. Recent clinical trials suggest that psychedelic‑assisted therapy using psilocybin or MDMA may offer rapid and durable...

DOI: 10.5281/zenodo.21893915

Exploratory non-randomized clinical trial of subcutaneous esketamine in treatment-resistant depression: Effects of ketamine-assisted psychotherapy

Journal of Affective Disorders August 10, 2026 Yves Martins Varela, Patrícia Cavalcanti-Ribeiro, Geovan Menezes de Sousa et al.

BACKGROUND: Ketamine is an effective rapid-acting treatment for treatment-resistant depression (TRD), producing antidepressant effects within hours of administration. Because it induces states of heightened neuroplasticity and psychological openness, psychotherapy may enhance its therapeutic effects. METHODS: This exploratory, nonrandomized, open-label clinical trial evaluated the adjunctive...

DOI: 10.1016/j.jad.2026.122369

Methodological fragmentation and integration priorities in psychedelic-assisted therapy assessment: a scoping review

Frontiers in Psychiatry August 6, 2026 Maria Laura Mele, Stefano Federici

IntroductionPsychedelic-assisted therapy (PAT) is an emerging complex intervention for psychiatric and existential conditions (i.e., forms of distress related to meaning, mortality, and identity, such as that arising in life-threatening illness); however, a systematic characterization of the evaluation methods used across the entire clinical intervention remains incomplete. This scoping review...

DOI: 10.3389/fpsyt.2026.1880744 Full text Psychedelic-assisted psychotherapy Psychedelic-assisted therapy Assessment methods Implementation science +2

Psilocybin-containing mushroom-assisted psychotherapy is associated with sustained psychological and somatic improvements: two case studies from Jamaica

Frontiers in Psychiatry July 29, 2026 Caitlyn Hanna Sams, Jasmine Davis, Anuradha Ramdas et al.

We report two case studies that examine the therapeutic potential of structured psilocybin-containing mushroom biomass regimens administered within a clinical framework, evaluating their impact on mental health outcomes as well as associated somatic symptoms. Two patients underwent the De La Haye Psilocybin Treatment Protocol (DPTP), which integrates micro- and high-doses (combined psilocybin...

DOI: 10.3389/fpsyt.2026.1876189

The Hidden Architecture of Psychedelic Therapy How Music Shapes Emotion, Imagery, Memory, Surrender, and Ketamine Tolerability A White Paper Based on 41 Studies of Music in Psychedelic-

Zenodo (CERN European Organization for Nuclear Research) July 21, 2026 Michael Alvear preprint

Music is often treated as an atmospheric accessory in psychedelic and ketamine therapy: useful, pleasant, optional, or merely calming. That framing is too weak. Across a curated evidence base of 41 studies, reviews, mechanistic papers, clinical reports, playlist-design papers, ketamine-specific studies, ceremonial-music papers, and counterarguments, music repeatedly appears as an active...

DOI: 10.5281/zenodo.21480416

Psychedelic-Assisted Psychotherapy Education at GSPP: Assessing PsyD Student and Alumni Interest, Attitudes, and Perceived Training Needs

July 16, 2026 Devon Seelig

Interest in psychedelic-assisted psychotherapy (PAP) is expanding rapidly within research, policy reform, and clinical application. Despite this rapid growth, formal training in PAP within accredited doctoral psychology programs is limited to nonexistent. This doctoral project aimed to assess interest in and attitudes toward PAP-related education among current students and alumni of the...

DOI: 10.56902/etdcrp.2026.20 Coursework Accreditation Training meteorology Professional development +5

Psychedelic therapy at the end of life: unexplored alternative to assisted suicide in the UK.

The British Journal of Psychiatry July 14, 2026 Ruslan Zinchenko

In this editorial, I examine the parallels between conventional and assisted suicide. Psychedelic therapy has been shown to alleviate end-of-life distress and reduce suicidality. I advocate for rescheduling psychedelics to enable research into their effectiveness as an adjunct to palliative care, prior to institutionalising assisted suicide in the UK.

DOI: 10.1192/bjp.2026.10729 Full text Assisted suicide Drug regulation Psychedelic drugs Terminal care

Changes in trauma symptoms of discrimination after MDMA-assisted psychotherapy for posttraumatic stress disorder.

Scientific Reports July 11, 2026 Monnica T. Williams, Sonya C. Faber, Jordan Sloshower et al.

This preliminary study explored the effects of MDMA-assisted therapy on trauma symptoms related to discrimination, as measured by the Trauma Symptoms of Discrimination Scale (TSDS). A total of five diverse participants, who experienced multiple types of discrimination (e.g., gender, racial/ethnic, social class, age, sexual orientation), were assessed before and after treatment. A paired-samples...

DOI: 10.1038/s41598-026-59333-w Full text MDMA Discrimination Oppression Trauma