MDMA has properties that may make it attractive for psychotherapy, although many of its effects are potentially problematic. These contrasting effects will be critically reviewed in order to assess whether MDMA could be safe for clinical usage. Early studies from the 1980s noted that MDMA was an entactogen, engendering feelings of love and warmth. However, negative experiences can also occur...
Výzkum je zaměřen na osoby, které se vydaly do amazonských pralesů užívat přírodní halucinogen ayahuasku v kontextu „šamanského“ rituálu. Tento jev popisovaný antropology od 70. let. 20. stol. jako tzv. „šamanský turismus“ je stále aktuálnější především mezi obyvateli zemí Evropy a USA. Našim cílem bylo zmapovat, jakým způsobem ayahuaskový šamanský turismus probíhá – motivaci osob, které tento...
This qualitative empirical study explores the ritual use of ayahuasca in the treatment of addictions. Ayahuasca is an Amazonian psychedelic plant compound created from an admixture of the vine Banisteriopsis caapi and the bush Psychotria viridis. The study included interviews with 13 therapists who apply ayahuasca professionally in the treatment of addictions (four indigenous healers and nine...
December 1, 2013Marcelo R. Malakooti, M. Friedman, Craig M. Smith
Introduction: New synthetic recreational drugs are associated with multi-organ system failure, serotonin syndrome, and even death. "25I" (25-NBOMe), also known as "Smiles" or "Nbomb," is a synthetic full agonist of 5-HT2A receptor. It has been used for psychedelic properties similar to LSD. There are few reports of this 25I toxicity in the literature. Toxic effects include hypertension,...
Ecstasy is a widely used recreational drug that usually consists primarily of 3,4-methylenedioxymethamphetamine (MDMA). Most ecstasy users consume other substances as well, which complicates the interpretation of research in this field. The positively rated effects of MDMA consumption include euphoria, arousal, enhanced mood, increased sociability, and heightened perceptions; some common...
A web-based survey was used to consult the opinions of experienced drug users on matters related to drug harms. We identified a rare sample of 93 drug users with personal experience with 11 different illicit drugs that are widely used in the UK. Asked to assess the relative harms of these drugs, they ranked alcohol and tobacco as the most harmful, and three "Class A" drugs (MDMA, LSD, and...
THE WILEY-BLACKWELL HANDBOOK OF Transpersonal Psychology "The new Handbook of Transpersonal Psychology is a necessity today. Many transpersonal psychologists and psychotherapists have been waiting for such a comprehensive work. Congratulations to Harris Friedman and Glenn Hartelius. May this book contribute to an increasingly adventurous, creative, and vibrant universe."—Ingo B. Jahrsetz,...
A wider array of treatments are needed for people with substance abuse disorders. Some psychedelic compounds have been assessed as potential substance abuse treatments with promising results. MDMA may also help treat substance abuse based on shared features with psychedelic compounds and recent reports indicating that MDMAassisted psychotherapy can reduce symptoms of PTSD. Narrative reports and...
N,N-dimethyltryptamine (DMT) is classified as a naturally occurring serotonergic hallucinogen of plant origin. It has also been found in animal tissues and regarded as an endogenous trace amine transmitter. The vast majority of research on DMT has targeted its psychotropic/psychedelic properties with less focus on its effects beyond the nervous system. The recent discovery that DMT is an...
The anaesthetic ketamine is used to treat various chronic pain syndromes, especially those that have a neuropathic component. Low dose ketamine produces strong analgesia in neuropathic pain states, presumably by inhibition of the N-methyl-D-aspartate receptor although other mechanisms are possibly involved, including enhancement of descending inhibition and anti-inflammatory effects at central...