International Journal of Human Sciences Research
March 7, 2022
Ana Cláudia Drumond de Araújo Lima, Eunaihara Lígia Lira Marques
This article aims to bring up the discussion about the possible effects of Psychedelic Therapy, that is, the use of psychoactive substances in the treatment of some resistant mental disorders. For this, such understandings were sought from the literature in the national and international context. It is noteworthy that there is a scarcity of studies and to understand the reason for this lack of...
Psychopharmacology
March 7, 2022
Aryan Sarparast, Kelan Thomas, Benjamin Malcolm et al.
85 citations
As MDMA and psilocybin continue to move through the FDA drug development process, this systematic review offers a compilation of existing research on psychiatric drug-drug interactions with MDMA or psilocybin.
Australian & New Zealand Journal of Psychiatry
March 4, 2022
Suresh Muthukumaraswamy, Anna Forsyth, Rachael Sumner
59 citations
With the extensive public, commercial and scientific interest from what has been widely termed the psychedelic renaissance, it is important that the scientific practices and results obtained from its implementation into medicine are put under a critical microscope. While there are numerous works on the potential benefits and applications of psychedelics as medicines, relatively little has been...
medRxiv
March 2, 2022
Maggie Kiraga, Kim P. C. Kuypers, Malin V. Uthaug et al.
preprint
Abstract Anxiety disorders are the most common type of psychiatric disorders among Western countries. Evidence-based treatment modalities including pharmacological and cognitive-behavioral therapy result in relatively low response rates (average range: 51 - 58%). Historical and recent research suggests psychedelic drugs may be efficacious in alleviating anxiety-related symptoms among healthy...
Journal of Psychopharmacology
March 1, 2022
Catherine Bird, A. H. Young
As we head into the (Northern Hemisphere) spring, the Journal publishes another set of papers which illustrate the robust health of the science of psychopharmacology. Once again, papers mostly focus on psychedelic drugs and related topics reflecting the zeitgeist (Young, 2022). de Wit et al. (2022) explore translational challenges and opportunities between clinical research and laboratory...
Clinical drug investigation
March 1, 2022
Anton L. V. Avanceña, J. Kahn, Elliot Marseille
19 citations
Intensive psychotherapy assisted with 3,4-methylenedioxymethamphetamine (MDMA-AT) was shown in Phase 3 clinical trials to substantially reduce post-traumatic stress disorder (PTSD) symptoms compared to psychotherapy with placebo. This study estimates potential costs, health benefits, and net savings of expanding access to MDMA-AT to eligible US patients with chronic and severe PTSD. Using a...
HAU: Journal of Ethnographic Theory
March 1, 2022
David Dupuis
15 citations
Although so-called “psychedelic” substances have recently experienced a revival of interest in their therapeutic properties, the underpinnings of their effectiveness remain poorly understood. Based on data collected during ethnographic fieldwork in a Peruvian Amazon clinic, this article proposes an anthropological approach to their therapeutic efficacy in the treatment of addiction. Using an...
Journal of Psychopharmacology
March 1, 2022
Gabrielle Agin-Liebes, Richard J. Zeifman, Jason B. Luoma et al.
51 citations
Background: Evidence suggests that psychedelic-assisted therapy carries transdiagnostic efficacy in the treatment of mental health conditions characterized by low mood and the use of avoidance coping strategies. Aims: While preliminary evidence suggests that psychological flexibility and emotion regulation processes play an important role within psychedelic therapy, this prospective study...
Neuropsychopharmacology
March 1, 2022
Deborah Rudin, John D. Mccorvy, Grant C. Glatfelter et al.
18 citations
Derivatives of (2-aminopropyl)indole (API) and (2-aminopropyl)benzofuran (APB) are new psychoactive substances which produce stimulant effects in vivo. (2-Aminopropyl)benzo[β]thiophene (APBT) is a novel sulfur-based analog of API and APB that has not been pharmacologically characterized. In the current study, we assessed the pharmacological effects of six APBT positional isomers in vitro, and...
Sexual & Relationship Therapy
February 28, 2022
Lucy Jacobs, S. Banbury, J. Lusher
Abstract Background: Research has predominated among the therapeutic application of psychedelics for varied psychopathologies and yet remains limited when supporting sexual behaviour intimacy among couples; particularly those who micro-dose. Method: Using semi-structured interviews, this qualitative study explored the micro-dosing sexual experiences of four partnered men and women aged 20–35...