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Journal for the Study of Religion, Nature and Culture January 25, 2008 Graham Harvey
Andy Letcher, Shroom: A Cultural History of the Magic Mushroom (New York: Ecco, 2007), 384 pp. Pbk. $25.95, ISBN 0-06-082828-5.
Pharmacology, Biochemistry, and Behavior January 2008 William E Fantegrossi, Chad J Reissig, Elyse B Katz et al.
N,N-dipropyltryptamine (DPT) is a synthetic tryptamine hallucinogen which has been used psychotherapeutically in humans, but has been studied preclinically only rarely. In the present studies, DPT was tested in a drug-elicited head-twitch assay in mice, and in rats trained to discriminate lysergic acid diethylamide (LSD), N,N-dimethyl-4-phosphoryloxytryptamine (psilocybin), or...
Pharmacology, Biochemistry, and Behavior January 2008 Jerrold C Winter
It has been observed that agents with agonist activity at 5-HT2A receptors prevent neurotoxicity induced by the non-competitive NMDA antagonist, dizocilpine (MK-801). Subsequent behavioral studies reported complete antagonism by LSD and DOM of the stimulus effects of the related NMDA antagonist, phencyclidine [PCP]. The present study sought to extend those observations to include other...
Mycobiology 2008 In‐kyoung Lee, Sung‐min Cho, Soon‐ja Seok et al. 32 citations
Gymnopilus spectabilis, a hallucinogenic mushroom belonging to the family Cortinariaceae, is found growing in dense clusters on stumps and logs of hardwoods and conifers. It contains the hallucinogenic alkaloid psilocybin and its strongly bitter taste makes it undesirable as an edible. In an effort to identify chemical constituents of Korean native wild mushrooms, 4,6-decadiyne-1,3,8-triol (1),...
Substance Use & Misuse 2008 Sarah Riley, Graham Blackman 36 citations
A survey of magic mushroom use was completed by 174 participants in 2004, a year when the sale of hallucinogenic mushrooms was not illegal in the UK. The data were collected in Edinburgh and Bristol (UK). Participants were a self-selecting convenience sample. Participants tended to be in their 20s, White-British, in education or employed; 64% were male. Participants reported a pattern of...
Pharmacology, Biochemistry, and Behavior October 2007 Danuta Marona‐lewicka, David E Nichols
Activation of 5-HT(2A) receptors is thought to mediate the hallucinogenic effects of LSD. Nevertheless, in a previous report we provided evidence that a delayed temporal phase of the behavioral pharmacology of LSD is mediated by D(2)-like dopamine receptor stimulation. In this study rats were trained to discriminate LSD with either a 30 min preinjection time (LSD-30, N=12) or a 90 min...
The Beauty of the Primitive July 1, 2007 Andrei A. Znamenski
Abstract This chapter looks at the relationship between shamanism and psychedelic culture, focusing on the experience of investment banker R. Gordon Wasson and his Russian-born wife, Valentina, with mushrooms. Valentina and Gordon eventually embarked on their lifelong quest to explore the role of mushrooms in the histories and folklore of different cultures. When Valentina died of cancer in...
Neuron February 1, 2007 Javier González-Maeso, Noelia V Weisstaub, Mingming Zhou et al.
Hallucinogens, including mescaline, psilocybin, and lysergic acid diethylamide (LSD), profoundly affect perception, cognition, and mood. All known drugs of this class are 5-HT(2A) receptor (2AR) agonists, yet closely related 2AR agonists such as lisuride lack comparable psychoactive properties. Why only certain 2AR agonists are hallucinogens and which neural circuits mediate their effects are...
Forensic Science International November 10, 2006 Takuro Maruyama, Nobuo Kawahara, Kazumasa Yokoyama et al.
"Magic mushroom (MM)" is the name most commonly given to psychoactive fungi containing the hallucinogenic components: psilocin (1) and psilocybin (2). We investigated the rRNA gene (internal transcribed spacer (ITS) and large subunit (LSU)) of two Panaeolus species and four Psilocybe species fungi (of these, two are non-psilocybin species). On the basis of sequence alignment, we improved the...
Pediatrics November 1, 2006 Rüssel S. Falck, Linna Li, Robert H. Carlson et al. 19 citations
To the Editor.—Dextromethorphan is the d-isomer of the codeine analog, levorphanol, and the active ingredient in >100 over-the-counter cough and cold preparations. Reports of dextromethorphan abuse date back to the 1960s.1,2 There is some evidence suggesting that when used inappropriately at very high doses (eg, 1500 mg/day), dextromethorphan can result in a dependence-like syndrome.2...