Research suggests that methylenedioxymethamphetamine (MDMA)/`ecstasy' can cause serotonin depletion as well as serotonergic neurodegradation that may result in depression. This longitudinal study used the Beck Depression Inventory (BDI-II) to assess depressive symptomatology every six months over a two-year period among a community sample of young adult MDMA/`ecstasy' users ( n = 402)....
To the Editor.—Dextromethorphan is the d-isomer of the codeine analog, levorphanol, and the active ingredient in >100 over-the-counter cough and cold preparations. Reports of dextromethorphan abuse date back to the 1960s.1,2 There is some evidence suggesting that when used inappropriately at very high doses (eg, 1500 mg/day), dextromethorphan can result in a dependence-like syndrome.2...
Although young people attending raves have been most visibly associated with the use of ecstasy and other "club drugs" in the United States, there is reason to believe that they are not a homogenous group in terms of their drug use practices. The purpose of this article is to begin developing a typology of young adult ecstasy users involved in the rave subculture--known as Ravers or Party Kids....
In the past several years, the use of MDMA (Ecstasy) has increased substantially in the United States and in many countries around the world. Although this increase has been associated with the dance club and rave scenes, Ecstasy use has expanded into new settings. At the same time, the diversity of people using the drug has also grown. Given the increasing, although unclear, evidence that MDMA...