Serotonergic psychedelics are advancing as psychiatric treatments, yet acute responses vary between individuals and the contribution of sex, a fundamental biological variable, remains largely unexamined. We pooled two double-blind, placebo-controlled studies in healthy volunteers (N = 72; 31 male, 41 female) comparing psilocybin 15 mg, 2C-B 20 mg, and LSD 50 μg. Linear mixed models tested sex...
Anomalous phenomena and associated experiential events have gained increasing scientific attention, yet the developmental organisation of such experiences across an individual’s life has rarely been examined systematically. This study presents a longitudinal analysis of a single experiencer’s encounters spanning nearly five decades, reconstructed from detailed narrative material and analysed...
The beginning of the twenty-first century has been marked by profound transformations in the ways reality, human beings, and society are understood. The rapid development of cognitive science, neuroscience, complexity theory, synergetics, quantum physics, digital technologies, and artificial intelligence has prompted a fundamental reconsideration of many traditional assumptions concerning the...
This study examines the features of religious experience in the Soka Gakkai (SG) compared with William James’s theory. Religious experiences in the SG are not as ‘mystical’ as those James describes. Daisaku Ikeda asserts that everyone should dedicate their full effort to resolving the problems they face. The doctrine of ‘voluntarily assuming the appropriate karma’ (gan-ken-o-go)...
How did religious poets contribute to ideas about religion, tolerance, and spiritual truth in the Mughal Empire? This dissertation examines the poetry of Feyżī (1547–1595), the poet laureate of the Mughal emperor Akbar. Feyżī wrote during a period in which Emperor Akbar promoted a vision of peaceful coexistence among people of different religious backgrounds, known as ṣulḥ-i kull ("universal...
Published in Scientific Reports (Nature Portfolio), this study extends inelastic electron tunneling spectroscopy (IETS)—originally proposed as a model for olfactory receptor activation—to the mammalian serotonin receptor (5-HT2A) through quantum-chemical modeling. It finds that several serotonin agonists, including LSD and DOI, share a common vibrational peak near 1500 cm⁻¹ whose intensity...
Acute stress impairs attention and procedural performance in high-acuity environments. Whether brief mindfulness-based interventions are feasible and affect performance in intensive care unit (ICU) simulation training is unknown. To evaluate the feasibility of a brief mindfulness-based intervention before simulated ultrasound-guided central venous access device (CVAD) insertion. Single-centre...
This research focuses on the symbols of mysticism and the psychology of mysticism in the novel Hilang Dalam Dekapan Semeru (Aditya, 2025). Mystical symbols such as the figure of a woman dressed in white, frankincense, offerings, dolls, free-range chicken eggs, seven-faced flowers, and the mystical experiences of climbers are analysed in the real world and the supernatural world in Javanese...
The study of consciousness has moved from the margins of philosophy to the center of theoretical physics. Yet, despite increasingly sophisticated mathematical and quantum models, ontological progress on the "Hard Problem" appears stalled. This paper does not claim to solve the Hard Problem, nor to establish a new metaphysics of mind. Instead, it advances a diagnostic framework showing that a...
In this chapter, the phenomenology of emotions in people with schizophrenia is explored. A nuanced understanding of the specific emotional challenges in schizophrenia, together with their transformative potential, can inform psychotherapeutic and rehabilitative approaches and help to uncover their healing dimensions. The first section of the chapter examines the emotional world of the person...