Neuroscience Letters
December 19, 1988
Pamela A. Pierce, Stephen J. Peroutka
The binding affinities of 3 ring-substituted amphetamine compounds were determined at 9 neurotransmitter binding sites in human cortex. (+/-)-3,4-Methylenedioxyamphetamine (MDA), (+/-)-3,4-methylenedioxyethamphetamine (MDE), and (+/-)-3,4-methylenedioxymethamphetamine (MDMA or 'Ecstasy') all display highest affinity (approximately 1 microM) for the recently identified 'DOB binding site' labeled...
The Journal of Nervous and Mental Disease
July 1, 1988
T E Oxman, S D Rosenberg, P P Schnurr et al.
To compare the subjective experience of different forms of altered states of consciousness, computerized content analysis was applied to 66 autobiographical accounts of schizophrenia, hallucinogenic drug states, or mystical ecstasy and to 28 autobiographical control accounts of important personal experiences. The patterns of lexical choice used by the four groups were significantly different in...
Pharmacology, Biochemistry, and Behavior
March 1988
Richard A Glennon, M Yousif, G Patrick
Using a standard two-lever operant procedure, groups of rats were trained to discriminate intraperitoneal doses of the phenylisopropylamines (+)amphetamine (1.0 mg/kg) or racemic 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM; 1.0 mg/kg) from saline using a VI 15-sec schedule of reinforcement for food reward. Once trained, the animals were administered doses of several methylenedioxy...
Medical toxicology and adverse drug experience
1988
J F Buchanan, C R Brown
'Designer drugs' are substances intended for recreational use which are derivatives of approved drugs so as to circumvent existing legal restrictions. The term as popularised by the lay press lacks precision. Contrary to the popular belief that 'designer drugs' are original creations, the majority of these agents are 'borrowed' from legitimate pharmaceutical research. They merely represent the...
Biochemical Pharmacology
December 1, 1987
M Johnson, Glen R. Hanson, James W. Gibb
The influence of N-ethyl-3,4-methylenedioxyamphetamine (MDE) on the central serotonergic and dopaminergic systems of the rat after a single or multiple injections was studied. MDE (10 mg/kg) produced a significant decrease in the concentration of 5-hydroxytryptamine (5-HT) 1 hr later in the frontal cortex and the hippocampus without affecting the concentration of 5-hydroxyindoleacetic acid...
Pharmacology, Biochemistry, and Behavior
October 1987
J W Boja, M D Schechter
Eight male rats were trained to discriminate 2.0 mg/kg N-ethyl-3,4-methylenedioxyamphetamine (MDE) from its vehicle using a two-lever, food-motivated operant discrimination task. Once trained, the rats showed a dose-dependent decrease in discriminative accuracy following administration of decreased doses of MDE (ED50 = 0.75 mg/kg). Administration of 1.5 mg/kg 3,4-methylenedioxymethamphetamine...
European Journal of Pharmacology
February 10, 1987
D M Stone, M Johnson, Glen R. Hanson et al.
Three psychoactive amphetamine congeners were evaluated for their ability to cause long-term changes in several neurochemical parameters indicative of central serotonergic function. Two weeks after multiple doses (10 mg/kg) of 3,4-methylenedioxyamphetamine (MDA) or its N-methylated derivative, 3,4-methylenedioxymethamphetamine (MDMA), selective and dramatic decreases were observed in regional...
Journal of Ethnopharmacology
June 1986
P A De Smet, N M Hellmuth
There are various enema scenes on classic Maya pottery, which undoubtedly represent rituals and may very well indicate that the ancient Maya took intoxicating enemas in a ritual context. This idea is quite contrary to the traditional view that the ancient Maya were a contemplative people, who did not indulge in ritual ecstasy. The occasional display of vomiting actors would seem to provide a...
Journal of Religion and Health
March 1, 1984
J R Haule
"Soul-making" (cf. Jung and Hillman) is the process of integrating spiritual and bodily imagery into an intimated wholeness transcending conscious comprehension. Pierre Janet's case of the psychotic mystic, Madeleine, reveals that the patient had been "making" her own-soul even though his theory had no provision for soul. Janet's soul-stripping theory is contrasted with a soul-making approach,...
Ethnologia Europaea
December 31, 1983
Hans Sebald
7 citations
Ideal-type shamanism is compared with Franconian folk magic. Franconia, a central province of Germany, experiences the end phase of a tradition of dualistic folk magic, including white and black witchcraft. While there are similarities between shamanism and Franconian magic - good or evil spirits amenable to magical manipulation, psychosomatic effects, "justice magic" -, differences prevail....