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TDR: The Drama Review September 1, 2025 Ronald Rose-Antoinette
The anarchic embrace of difference in the encounters of and variations on Western and non-Western spiritual practices in Martinique reveals ways of disrupting the univocal, linear, and centralizing violence of plantation society. Examining the various techniques of collective ecstasy through song, dance, and other sacramental signs of spirit possession calls attention to anticolonial models of...
The Journal of Clinical Psychiatry September 1, 2025 Vania Modesto-Lowe, Deanna Sgambato, Pa-C Margaret Chaplin
To the Editor: Psychedelic-assisted therapy (PAT) combines psychedelics, such as psilocybin, with guided psychotherapeutic support. 1 These substances interact with patient's mindset ("set") and the surrounding environment ("setting"), 2 making the context of the experience a critical factor in therapeutic outcomes.As these substances gain recognition for their therapeutic potential, it is...
Pharmaceutical Science August 27, 2025 Guilllermo Castaño-perez, Sara Isabel Castaño-ocampo
The resurgence of research on the use of psychedelic substances for the treatment of mental disorders and addictions has generated significant interest in the scientific and clinical communities. This chapter examines the current evidence on the efficacy, safety, and limitations of psychedelics in the treatment of these conditions. Studies investigating the use of psychedelics as monotherapy...
Psychedelics August 26, 2025 Harriet de Wit
Professor Harriet de Wit, a pioneering researcher in psychoactive drugs at the University of Chicago, shares her remarkable 45-year scientific journey in this illuminating Genomic Press Interview. As Director of the Human Behavioral Pharmacology Laboratory and recipient of prestigious honors including the 2019 European Behavioral Pharmacology Society Distinguished Investigator Award, Dr. de Wit...
ACS Omega August 26, 2025 Roman Boča, Juraj Štofko, Cyril Rajnák
Small molecules containing phenyl and aliphatic amine groups belonging to psychotropic drugs were studied by quantum chemical computational methods. Each of the 9 studied species (phenethylamine, amphetamine, ephedrine, pseudoephedrine, methamphetamine, MDMA, MDEA, MDA, MDAI) was considered in three oxidation states: neutral molecule, molecular cation, and molecular anion. Protonated residues...
Research Square August 22, 2025 Richard J. Zeifman, George Danias, Gabrielle Agin-Liebes et al. 2 citations preprint
Abstract Background: Psychedelics can acutely induce mystical experiences and elevated positive mood, which may contribute to the potential benefits of psychedelic therapy. However, there remains limited understanding of the occurrence and importance of specific positive emotional experiences within psychedelic therapy. Therefore, we examined the effects of psychedelics on positive emotional...
Brain Sciences August 21, 2025 Dean Bilenker, Nicole M. Avena 2 citations
Recent advances in psychedelic research have renewed interest in their therapeutic potential for psychiatric disorders characterized by cognitive and behavioral rigidity. This review examines the rationale for using serotonergic psychedelics—particularly 5-HT2A receptor agonists such as psilocybin—in the treatment of eating disorders (EDs), including anorexia nervosa (AN), bulimia nervosa (BN),...
NPP Digit Psychiatry Neurosci August 20, 2025 Albert Garcia‐romeu 2 citations
Interest in “psychedelic therapies,” using substances such as ketamine, 3,4-methylenedioxymethamphetamine (MDMA), and psilocybin to treat psychiatric conditions, has grown steadily in recent years. Although pharmacologically distinct and functioning via differential mechanisms, these drugs are broadly classified as hallucinogenic, meaning they are thought to produce hallucinations. However,...
Brazilian Journal of Implantology and Health Sciences August 14, 2025 A. Silva, Érika Barros Teixeira da Cruz, Samuel Cândido Freres et al.
O transtorno de estresse pós-traumático (TEPT) é uma condição psiquiátrica caracterizada por sintomas persistentes após vivência de eventos traumáticos, incluindo revivescências, hipervigilância e esquiva. Estudos recentes têm apontado o uso de psicodélicos, como MDMA e psilocibina, como potenciais coadjuvantes no tratamento, devido à sua capacidade de promover neuroplasticidade e facilitar a...
Psychiatry and Clinical Psychopharmacology August 14, 2025 Nadav Liam Modlin, Jessica L Maples-Keller, Maria Sarang et al.
Background: Current trauma treatment options often fail to meet patients' needs. Despite the availability of established interventions, many trauma treatments fail to adequately meet patients' needs. In parallel, there has been renewed scientific and public interest in the therapeutic potential of psychedelics and related compounds, accompanied by increasing unsupervised use. This underscores...