Page 23 of 346: studies 221 to 230 of 3,454, newest first. Back to the MDMA overview
The American Journal of Bioethics January 13, 2025 Jamie Beachy, Willa Hall, Chantelle Thomas et al. 2 citations
As research therapists with hundreds of hours of clinical experience supporting adults with PTSD in Phase 3 trials of MDMA assisted-therapy (MAT), we appreciate the opportunity to respond to this s...
Progress in Neuro-Psychopharmacology and Biological Psychiatry January 10, 2025 Dan Xu, Akifumi Eguchi, Rumi Murayama et al. 4 citations
3,4-Methylenedioxymethamphetamine (MDMA; Ecstasy) is a widely abused recreational drug that has also gained interest for potential clinical applications in mental health. With the growing recognition of gut microbiota's role in mental health, this study examined whether repeated oral MDMA administration could affect gut microbiota in the small intestine, cecum, and colon of male rats. Repeated...
2025
Why do people seek a connection to something beyond the social dimensions of the world? Ecstatic experiences are often labelled religious, spiritual, mystical or even sacred. However, ecstasy is not just extraordinary; for many people throughout the world it is an ordinary part of daily life. The Handbook highlights the diverse individuals who have experienced ecstasy in the past and present...
Cadernos de Prospecção 2025 Rachel Lais Brandão Viana, Maria Hosana Conceição
Este artigo tem como objetivo realizar uma revisão bibliográfica a respeito da utilização clínica do 3,4-Metilenodioximetanfetamina (MDMA ou Ecstasy) em sessões de psicoterapia do Tratamento do Transtorno de Estresse Pós-Traumático (TEPT). Esse distúrbio é comumente tratado com antidepressivos, que atuam sobre neurotransmissores, além do acompanhamento psicoterapêutico, no entanto, alguns...
Addiction and Health 2025 Mohadese Kamali, Hoda Kamali, Arezoo Saberi et al.
Methamphetamine is a common addictive industrial substance. Medicinal plants such as Artemisia absinthium L. with anti-inflammatory, antioxidant, analgesic, neuroprotective, antidepressant, and antipyretic properties may help patients reduce withdrawal syndrome symptoms. Five treatment groups received intraperitoneal (i.p.) injections of 3,4-methylenedioxymethamphetamine (MDMA) and an ethanolic...
Frontiers in Psychiatry 2025 Rocco Miazzi, Clara Cestonaro, Silvia Righetto et al.
This structured review critically examines the psychological and neuropsychological effects of MDMA (3,4-methylenedioxymethamphetamine) use during adolescence, focusing exclusively on human studies. MDMA is a widely consumed psychoactive substance among adolescents, particularly in social and recreational contexts. Drawing on 14 eligible studies identified through a comprehensive literature...
PLoS One 2025 Filip Stanicic, Vladimir Zah, Dimitrije Grbic et al. 5 citations
3,4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) is currently being evaluated for treatment of patients with moderate or higher severity post-traumatic stress disorder (PTSD). To provide a comprehensive summary of investigational MDMA-AT and current treatments for PTSD. A search was conducted in PubMed and Embase (December 20, 2023). Populations included adults with chronic,...
American Journal of Psychiatry 2025 Aaron Wolfgang, Gregory A. Fonzo, Joshua C. Gray et al. 47 citations
MDMA (i.e., 3,4-methylenedixoymethamphetamine), commonly known as "Ecstasy" or "Molly," has been used since the 1970s both in recreational and therapeutic settings. The Food and Drug Administration (FDA) designated MDMA-Assisted Therapy (MDMA-AT) as a Breakthrough Therapy for posttraumatic stress disorder (PTSD) in 2017, and the FDA is requiring an additional phase 3 trial after rejecting the...
Frontiers in Psychiatry 2025 Dimitri Perivoliotis, Kayla Knopp, Shannon Remick et al. 2 citations
Although effective evidence-based trauma-focused psychotherapies for posttraumatic stress disorder (PTSD) are available, a significant proportion of patients show a suboptimal response or do not complete them. MDMA-assisted therapy (MDMA-AT) for PTSD is a promising intervention currently being evaluated in numerous studies worldwide, including investigation for potential Food and Drug...
Frontiers in Psychiatry 2025 Alexa E Albert, Anthony L. Back 5 citations
Pathological narcissism (PN) is a complex, treatment-resistant disorder characterized by unstable self-esteem that fluctuates between grandiosity and vulnerability, complicating the formation of a stable self-image. With few empirically supported therapies, treatment has traditionally relied on long-term psychoanalytic approaches, but these often face high attrition. Recent research suggests a...