Addiction
January 30, 2025
Theodore Piper, Francesca Small, Michael Kelleher et al.
27 citations
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its quality; and to offer recommendations for...
Pharmaceuticals
January 19, 2025
Marco Bonaso, Letizia Biso, Benedetta Zucchini et al.
13 citations
Psychedelics, historically celebrated for their cultural and spiritual significance, have emerged as potential breakthrough therapeutic agents due to their profound effects on consciousness, emotional processing, mood, and neural plasticity. This review explores the mechanisms underlying psychedelics’ effects, focusing on their ability to modulate brain connectivity and neural circuit activity,...
Journal of Affective Disorders
January 15, 2025
Jia-Ru Li, Kuo-Tung Chiang, Yu-Chen Kao et al.
1 citation
Different study designs of psychedelic trials may impact the blinding and expectance, leading to biased treatment effects. This study aimed to examine the association between antidepressant efficacy and study designs in psychedelic trials. Six databases were systematically searched. Eligible trials were required to investigate the efficacy of psychedelics (psilocybin, lysergic acid diethylamide...
Comparative philosophy of religion
2025
Thorsten Botz-Bornstein
1 citation
AbstractMysticism is mostly employed in the context of theistic religions because historically, mysticism aims at a unification with God. It must be clarified if the project of comparative mysticism that this book suggests can be properly carried out when including non-theistic religions. The chapter examines phenomena such as quietism, ekstasis, and contemplation. Further, the relationship...
Figshare
2025
Daniel J. Kruger, Gina Mersereau, Ashley Sullivan et al.
preprint
Abstract Background The use of psychedelics is currently increasing in the United States. Awareness of clinical trials investigating the therapeutic applications of psychedelics may result in a record number of people who use psychedelics for the first-time. This study aimed to develop a harm-reduction resource to facilitate safe and successful psychedelic experiences outside of regulated...
Current Addiction Reports
2025
Nina Abukahok, Nicole D. Fitzgerald, Joseph J Palamar
Tusi, also known as "pink cocaine," has emerged across nightlife scenes in Latin America, Europe, Australia, and the United States (US). Tusi is typically a drug mixture containing ketamine and 3,4-methylenedioxymethamphetamine (MDMA). Due to tusi's inconsistent chemical makeup, surveillance and harm reduction efforts have proven difficult for researchers and consumers alike. This review...
Therapeutic Advances in Psychopharmacology
2025
Diana McHerron, Michaela Barber, Rachel Ham et al.
Physical touch is often included as a supportive or therapeutic tool in psychedelic-assisted therapy (PAT), involving instrumental forms of physical contact, supportive touch and somatic techniques. However, participants under the influence of psychedelics have reduced capacity to provide consent, are more suggestible and may experience and interpret therapeutic touch in ways they did not...
Frontiers in Psychiatry
2025
Julia Marek, Magdalena Domek-Gumprecht, Agata Macionga et al.
PolDrugs is a biennial epidemiological study aimed at analyzing patterns of mostly illicit psychoactive substance use in Poland in the context of psychiatry and harm reduction. This survey was held for the third time, and its results were compared to the last two editions. The survey was conducted as an online survey with 37 closed-ended single-choice questions and 3 multiple-choice questions....
International review of neurobiology
2025
Tijmen Bostoen, Stephan Tap, Joost J. Breeksema et al.
1 citation
Post-Traumatic Stress Disorder (PTSD) is a severe psychiatric condition that develops after exposure to trauma such as combat, natural disasters, or assault. It is characterized by re-experiencing trauma, avoidance, hyperarousal, and negative alterations in cognition and mood. Since its formal inclusion in the Diagnostic and Statistical Manual of Mental Disorders (DSM)-III in 1980, PTSD has...
Frontiers in Psychiatry
2025
Ella van Beers, Irene de Vries, Caroline Planting et al.
2 citations
Many people with eating disorders report having experienced childhood maltreatment or a traumatic event prior to developing an eating disorder. Although many people with eating disorders have significant traumatic exposure or symptoms of post-traumatic stress disorder, very little research has examined the effects of combined treatments for this group. The purpose of this systematic review was...