Psychopharmacology
1986
R A Lyon, Richard A Glennon, M Titeler
3,4-Methylenedioxymethamphetamine (MDMA), 3,4-methylenedioxy-amphetamine (MDA), and their optical isomers, were assayed for their affinities at radiolabeled brain serotonin (5-HT1, 5-HT2) and dopamine (D2) binding sites. (R(-)-MDA and R(-)-MDMA displayed moderate affinities for 3H-ketanserin-labeled 5-HT2 sites (Ki = 3425 and 3310 nM, respectively) whereas the affinities for their...
Journal of Psychoactive Drugs
July 1, 1985
June E. Riedlinger
26 citations
(1985). The Scheduling of MDMA: A Pharmacist's Perspective. Journal of Psychoactive Drugs: Vol. 17, No. 3, pp. 167-171.
Scripta Instituti Donneriani Aboensis
1982
Hans Hof
1 citation
Phenomena such as ecstasy and mysticism display both psychological and physical features. The purpose of this paper is finding and understanding the structures in human consciousness which characterise the experience of certain kinds of ecstasy. The context in which this task is performed is an outline of fundamental changes in consciousness brought about by those methods of meditation which,...
Anatomy Journal of Africa
1970
B.J Oloruntola, P.A Adeniyi, A.O. Ishola et al.
Neurotoxicity of 3, 4-Methylenedioxymethamphetamine (MDMA, ecstasy) is still controversially discussed. MDMA is an amphetamine derivative that has gained significant popularity in recent years and has become the recreational drug of choice for many young, adolescents and adults. This study sought to investigate that MDMA causes a behavioral, biochemical and neurocytoarchitechural change in male...
JAMA
March 7, 1964
Roy R. Grinker
16 citations
For several years, quietly and without publicity, several scientists have been studying the behavioral pharmacology of lysergic acid diethylamide (LSD-25), and lately psilocybin, on experimental animals and human subjects. The psychotic effects of these drugs have some but not complete similarity to the schizophrenic psychoses, which has resulted in their classification as psychomimetics. Yet...
Journal of Addiction Medicine
Kevin H. Yang, Wayne Kepner, Anamika Nijum et al.
11 citations
3,4-Methylenedioxymethamphetamine (MDMA) (also known as "ecstasy" or "Molly") has regained attention in recent years for its efficacy in treating posttraumatic stress disorder, and the drug was granted breakthrough therapy designation for such use by the US Food and Drug Administration in 2017. However, little is known about the current epidemiology of recreational ecstasy/MDMA use. We...
American Journal of Therapeutics
Kenneth Shinozuka, Burton J. Tabaac, Alejandro Arenas et al.
After becoming notorious for its use as a party drug in the 1980s, 3,4-methylenedioxy-methampetamine (MDMA), also known by its street names "molly" and "ecstasy," has emerged as a powerful treatment for post-traumatic stress disorder (PTSD). There are extensive data about the risk profile of MDMA. However, the literature is significantly biased. Animal models demonstrating neurotoxic or adverse...
November 30, 2026
Frances Clemente
Abstract The book investigates the notion of ecstasy in Italian culture and literature between 1861 and 1915. Combining historical and cultural investigation with literary analysis, it traces the circulation and spreading of ecstatic phenomena in a variety of different discourses, specifically, those related to religion, science, and ‘occulture’, and the ways they were portrayed by Italian...
Ana Lilian Reyes, Brittany Michael, Tessy Korah
preprint
Abstract The street drug Molly, the crystal or powder form of MDMA (3,4-methylenedioxymethylamphetamine) is commonly ingested via oral or pulmonary routes. Intravenous administration of MDMA is rare and here we report a case of penile dorsal vein injection of Molly, development of penile abscess, and subsequent psychotic symptoms in a patient with a history of polysubstance use. A 60-year-old...
James W. B. Elsey, Vivi Anna Felicia Wuestman, Anouk Fieten
preprint
Background. Previous research has focused on risks associated with non-clinical MDMA use, contrasting short-sighted hedonistic motivations with negative long-term consequences. User perceptions may be more nuanced, incorporating numerous underexplored positive long-term effects. We aimed to: (1) Assess MDMA user perceptions regarding both positive and negative long-term effects, and (2)...