Psychedelic research is said to be going through a renaissance with widespread public and political attention on psychedelics' ability to clinically resolve various medicalized issues.The prevailing cultural narrative of psychedelics almost touts it as a panacea when used in regulated, clinical settings under the supervision of a trained guide.While clinical studies are certainly informative,...
BACKGROUND: Regular ingestion of sub-hallucinogenic doses of psychedelics, referred to as "microdosing", has gained increasing popularity and attention in the press and in online forums, with reported benefits across multiple cognitive and emotional domains. Rigorously controlled studies to date, however, have been limited in scope and have failed to produce results comparable to those reported...
Background: With support from the Radcliffe Institute for Advanced Study at Harvard University, we convened researchers representing palliative care, psychosocial oncology, spiritual care, oncology, and psychedelic-assisted therapies. We aimed to define priorities and envision an agenda for future research on psychedelic-assisted therapies in patients with serious illness. Over two days in...
Introduction Depression is one of the most prevalent mental illnesses, leading to important personal distress and economic consequences. Treatment is long, often involving psychotherapy and pharmacological treatment, and relapses are frequent. Used mostly for treatment of mood disorders and alcohol dependence, drugs such as lysergic acid diethylamide (LSD) were studied in the 1950’s and showed...
European PsychiatryApril 1, 2021R. Pinilla, Carmen Rocamora Rodriguez, D. Batet-Sanchez et al.3 citations
Introduction Ayahusca has potential therapeutic beneffits. Objectives Expose the potential beneffits of ayahuasca from neuropharmacology and clinical existing evidence. Methods A literature review was carried out in the databases pubmed, clinical key and texts of scientific dissemination. Results There´s scientific literature about the potential therapeutic use of ayahuasca in dependencies,...
Resume Decouvert en 1943 par le chimiste suisse Albert Hofmann, le LSD fut rapidement reconnu pour ses effets therapeutiques, notamment dans le cadre de la fin de vie. Puissant antalgique, il permettait aux patients en phase terminale de cancer d’apprehender leur propre mort avec plus de serenite et favorisait la communication avec les proches et le personnel soignant. Faisant partie des...
M r.P, age 65, has a history of major depressive disorder (MDD), gen- eralized anxiety disorder, and social phobia.Mr. P's personality is high in neuroticism and he has often responded to new situations with feelings of impending doom.For him, fear, anxious rumination, helplessness, and catastrophizing are familiar mental processes.When he was in his 30s, Mr. P had a severe major depressive...
Diseases that threaten life raise existential questions that can be a source of psychological distress. Studies with psychedelics demonstrate therapeutic effects for anxiety and depression associated with life-threatening illnesses. Ayahuasca has been proposed as a possible therapeutic agent in the treatment of psychiatric disorders. Preliminary studies suggest that ayahuasca could promote...
Abstract The success of modern medicine creates a growing population of those suffering from life-threatening illnesses (LTI) who often experience anxiety, depression, and existential distress. We present a novel approach; investigating MDMA-assisted psychotherapy for the treatment of anxiety in people with an LTI. Participants with anxiety from an LTI were randomized in a double-blind study to...
ScienceSeptember 25, 2020A. Nieder, Lysann Wagener, Paul Rinnert
Consciousness shared Humans have tended to believe that we are the only species to possess certain traits, behaviors, or abilities, especially with regard to cognition. Occasionally, we extend such traits to primates or other mammals—species with which we share fundamental brain similarities. Over time, more and more of these supposed pillars of human exceptionalism have fallen. Nieder et al....