PsyArXiv Preprints
October 22, 2026
preprint
Background: Subjective experiences featuring altered self-awareness, temporal perception, or spatial boundaries—termed Non-Ordinary Experiences (NOEs)—occur across clinical neurology, psychiatry, and psychedelic medicine, including in insular ecstatic seizures, meditation, breathwork, hypnosis, and psychedelic therapy. Objective: To synthesize neurobiological and clinical literature on NOEs for...
World Journal of Pharmaceutical Research
October 16, 2026
2Dr. Suman Sarkar *1Dr. Mukesh Kumar
preprint
Background: The clinical apparatus of Ayurveda is commonly understood through the lens of Laukiki Cikitsa (worldly therapeutics), which works primarily to restore bio-humoral equilibrium using pharmacological substances (Yuktipavyapasraya), spiritual rituals (Daivavyapasraya), and disciplined mental restraint (Sattvavajaya). Nevertheless, the foundational tantrakaras recognized that therapeutic...
The oncologist
October 15, 2026
Keenan Wills Davis, Michelle C. Bach, JoEllen Schimmels et al.
Psychedelic-assisted therapy (PAT) is increasingly discussed as a potential intervention for anxiety, depression, and existential distress among patients with advanced cancer. Yet the ethical challenges of PAT for patients approaching the end of life remain underdeveloped, particularly for oncologists who may be asked to counsel patients or consider referral to clinical trials. This article...
Lviv University Herald Series Psychological sciences
October 12, 2026
Ruslan Hanushchak, Игорь Прись
У статті здійснено ретроспективний огляд розвитку психоделічної терапії та проаналізовано сучасний стан досліджень її ефективності у лікуванні психічних розладів. Простежено еволюцію використання психоделічних речовин – від традиційних духовних і лікувальних практик корінних народів через ранні клінічні дослідження середини ХХ століття до сучасного етапу, так званого «психоделічного ренесансу»....
Surgical Neurology International
October 9, 2026
Andrea Garcia-Bitar, Eduardo Jesus Castañeda, José Rafael Buenrostro-Rangel et al.
Background: Neurosurgical patients carry a high and frequently undertreated burden of psychological suffering, acute and chronic pain, and neurological deficits amenable to recovery. The resurgence of psychedelic research has produced relevant evidence in adjacent fields, but its applicability to neurosurgery has not been systematized. This review synthesizes that evidence across prevention,...
Therapeutic Advances in Psychopharmacology
October 8, 2026
Gianluca A. Florineth, Anna L. Boeker, Felix Müller et al.
Background Classic psychedelics show potential for treating psychiatric disorders, yet the psychological framework of psychedelic-assisted therapy (PAT) remains underspecified. As regulatory approval approaches, defining the contribution of psychological interventions to clinical outcomes is critical for both mechanism inference and implementation. Objectives To systematically review the...
Revista brasileira de neurologia
October 1, 2026
Fabricio Hampshire, Marleide da Mota Gomes, Christian Naurath et al.
Background: Neurospirituality is an emerging interdisciplinary framework integrating neuroscience, neurology, palliative care, and the medical humanities to address the spiritual and existential dimensions of health. Spirituality refers to meaning-making through connectedness beyond the self, whereas religiosity denotes organized beliefs, rituals, and communities. Objective: To review the...
IGI Global eBooks
September 22, 2026
Srishti Muralidharan, Navya Charan
Anguish represents a profound form of human suffering that extends beyond ordinary emotional distress and engages interconnected neurobiological, cognitive and physiological systems. This chapter conceptualizes anguish as an active, embodied state characterised by persistent emotional arousal, self-referential processing, autonomic dysregulation, and meaning-making efforts. Drawing on...
Journal of Pain and Symptom Management
September 18, 2026
Megan Miller, Molly Meyers, Candace Oglesby-Adepoju et al.
Psilocybin-assisted therapy (PAT) shows promise for alleviating psychological and existential distress among people with cancer; however, research is limited by homogeneous samples, raising concerns about generalizability and equity. To explore perceptions and attitudes of PAT among a subset of people with cancer who have been underrepresented in research. A qualitative descriptive study was...
International Journal of Independent Research Studies
September 11, 2026
Eric P. Rubenstein
Ketamine is increasingly used in psychiatric and psychotherapeutic treatment through intravenous, intranasal, sublingual or buccal, and subcutaneous administration. Its therapeutic applications extend beyond formally diagnosed psychiatric disorders and include existential anxiety, persistent emotional distress, trauma-related suffering, psychological responses to serious illness or major life...