Trials
April 4, 2017
Amy Mcandrew, Will Lawn, Tobias Stevens et al.
20 citations
BACKGROUND: Worldwide, alcohol abuse is a burgeoning problem. Abstinence is key to allow recovery of physical and mental health as well as quality of life, but treatment for alcohol dependence is associated with high relapse rates. Preliminary data have suggested that a combined repeated ketamine and psychological therapy programme may be effective in reducing relapse in severe alcohol use...
Journal of Attention Disorders
April 1, 2017
Marc-Andreas Edel, Tanja Hölter, Kristina Wassink et al.
Objective: To compare a novel “third wave” mindfulness-based training program with an established skills training derived from dialectical behavior therapy, to reduce ADHD symptoms and improve mindfulness and self-efficacy. Method: Ninety-one adults with ADHD (combined and inattentive type, mainly medicated) were non-randomly assigned to and treated within a mindfulness-based training group...
The FASEB Journal
April 1, 2017
Melodi Ann Bowman, Melissa Vitela, W. Anthony Owens et al.
Twenty percent of adults are diagnosed with major depressive disorder, which is typically treated with selective serotonin reuptake inhibitors. However, this type of medication takes approximately six weeks to produce therapeutic effects. Recently, low doses of ketamine, a noncompetitive N‐methyl‐D‐aspartate (NMDA) receptor antagonist, have been shown to produce rapid and long‐lasting...
Behaviour Research and Therapy
April 2017
J Cobb Scott, Gerlinde C. Harb, Janeese A. Brownlow et al.
Posttraumatic stress disorder (PTSD) is associated with cognitive deficits in attention, executive control, and memory, although few studies have investigated the relevance of cognitive difficulties for treatment outcomes. We examined whether cognitive functioning and history of traumatic brain injury (TBI) were associated with response to cognitive-behavioral therapy (CBT) for PTSD-related...
Journal of Consulting and Clinical Psychology
April 2017
Chloe C Boyle, Annette L Stanton, Patricia A Ganz et al.
Mindfulness meditation reduces psychological distress among individuals with cancer. However, mechanisms for intervention effects have not been fully determined. This study tested emotion regulation strategies as mediators of intervention effects in a sample of younger women treated for breast cancer, a group at risk for psychological distress. We focused on two distinct strategies targeted by...
The FASEB Journal
April 1, 2017
Michael P Trahan, Sebastian Leth-Petersen, William E Fantegrossi
R (−)‐2,5‐Dimethoxy‐4‐iodoamphetamine (DOI) and other compounds with agonist affinity for serotonergic 5‐HT2A receptors are hallucinogenic drugs of abuse, but also have therapeutic potential in numerous neuropsychiatric conditions, including major depressive disorder, post‐traumatic stress disorder, and in the treatment of migraine and cluster headaches. Thus, commonly abused hallucinogens...
European Journal of Neurology
April 2017
Francesco Pagnini, Anna Marconi, Aurora Tagliaferri et al.
Studies investigating psychological interventions for the promotion of well-being in people with amyotrophic lateral sclerosis (ALS) are lacking. The purpose of the current study was to examine the use of an ALS-specific mindfulness-based intervention for improving quality of life in this population. A randomized, open-label and controlled clinical trial was conducted on the efficacy of an...
The FASEB Journal
April 1, 2017
Thomas W. Flanagan, Melaine N. Sebastian, Charles D. Nichols
2 citations
Only recently has the full therapeutic value of serotonin [5‐hydroxytryptophan (5‐HT)] receptor activation begun to be explored. Currently there are two 5‐HT 2A receptor agonists in human clinical trials for the treatment of depression and obesity. An exciting new therapeutic avenue in which 5‐HT 2A agonists might be employed is the modulation of inflammation in allergic airways disease. Our...
Spiral (Imperial College London)
April 1, 2017
Mendel Kaelen
10 citations
This research investigated how psychedelics and music work together in the brain and modulate subjective experience. Chapter 1 highlighted the prominent role of music in psychedelic therapy in the 1950s and 1960s, and how music continues to be used in modern psychotherapeutic trials with psychedelics. Although ‘psychedelic therapy’ shows promising findings for mental health care, little is...
Mindfulness
March 29, 2017
Laura G. Kiken, Kristjen B Lundberg, Barbara L. Fredrickson
Mindfulness and savoring the moment both involve presently occurring experiences. However, these scientific constructs are distinct and may play complementary roles when predicting day-to-day positive emotions. Therefore, we examined the unique and interactive roles of dispositional mindfulness and perceived ability to savor the moment for predicting daily positive emotions as well as related...