Background: Mental health is a significant component of academic achievement, while psychological distress can reduce academic performance. Objectives: The present study aimed to investigate the effect of Mindfulness-based Cognitive Therapy (MBCT) on subjective well-being and psychological distress of Kerman University of Medical Sciences students. Methods: In this quasi-experimental study, the...
In recent years, work-related stress has grown exponentially and the negative impact that this condition has on people's health is considerable. The effects of work-related stress can be distinguished in those that affect workers (e.g., depression and anxiety) and those that affect the company (e.g., absenteeism and productivity). It is possible to distinguish two types of prevention...
Theoretical and empirical work suggesting associations between (1) mindfulness and depression and (2) cognitive biases (CBs) and depression lay the groundwork for novel questions about how to model mindfulness, how mindfulness and CBs are linked, how CBs are associated with one another, and how CBs may explain the association between mindfulness and depression. The present study derived a model...
This project is a systematic review that highlights how beneficial psychedelic psychotherapy can be to those suffering with mental illness. The three mental illnesses chosen to be analyzed in the literature were depression, post-traumatic stress disorder (PTSD), and anxiety. The drugs used in the specific articles included Psilocybin, Ayahuasca(DMT), and MDMA (3,4-methylenedioxymethamphetamine;...
Discovered in the United States of America (USA) in the 1960s, ketamine was introduced as an anaesthetic drug to specifically replace phencyclidine. Briefly, the substance moved from the medical world to recreational users, since it was discovered that intense psychedelic experiences were obtained with dosages lower than those prescribed for anesthesia. At the end of the 90's, circulated in...
The active hallucinogen of magic mushrooms, psilocin, is being repurposed to treat nicotine addiction and treatment-resistant depression. Psilocin belongs to the tryptamine class of psychedelic compounds which include the hormone serotonin. It is believed that psilocin exerts its effect by binding to the serotonin 5-HT2A receptor. However, recent in-vivo evidence suggests that psilocin may...
This document details an authors' response to a critique of their work entitled: Skepticism About Recent Evidence that Psilocybin Opens Depressed Minds.
In healthy adults, LSD produces little change in cognition, mood There have been numerous anecdotal reports of beneficial mood and cognitive effects from repeated administration of low doses of lysergic acid diethylamide (LSD) at intervals of 3 to 4 days, but few controlled studies have been conducted. Animal research has suggested that repeated low doses of LSD could confer antidepressant...
Abstract Subanesthetic-dose racemic ( R,S )-ketamine (ketamine) produces rapid, robust, and sustained antidepressant effects in major depressive disorder (MDD) and bipolar disorder (BD) and has also been shown to effectively treat neuropathic pain, complex regional pain syndrome, and post-traumatic stress disorder (PTSD). However, to date, its mechanism of action remains unclear. Preclinical...
Subanesthetic doses of ketamine produce rapid and sustained anti-depressant effects in patients with treatment-resistant depression. Unfortunately, the usefulness of ketamine as a treatment is limited by its potential for abuse because of psychotropic side effects such as dissociation. Understanding the brain dynamics and the neural circuits involved in ketamine’s effects could lend insight...