Topics in spinal cord injury rehabilitation
2026
Radha Korupolu, Chelsea G Ratcliff, Shrasti Lohiya et al.
This study evaluated the feasibility and acceptability of an app-guided mindfulness meditation (MM) intervention compared to a health education (HE) control for individuals with spinal cord injury (SCI) and chronic pain. A pilot randomized controlled trial recruited 60 individuals with SCI and chronic pain from local SCI outpatient clinics, national registries, and community outreach....
Clinical ophthalmology
2026
Michael Huang, Jason Sheng, Brian Yu et al.
Those diagnosed with eye disease are at a higher risk for experiencing a decreased quality of life (QOL). Meditation and breathing exercises have been linked with improvements in this area, but research in populations of eye disease patients is relatively scarce. We aim to bridge this knowledge gap by synthesizing the available evidence on the effects of meditation and breathing exercises on...
Frontiers in Neuroscience
2026
Sabrina Diny, Fabian Schmidt, Andreas Wutz et al.
Mental disorders pose a major and growing challenge for health care systems worldwide, marked by persistent treatment gaps and limited access to psychotherapeutic care. Mind-body interventions such as mindfulness and relaxation practices are widely used in clinical contexts as low-threshold strategies to support stress regulation and psychological well-being. Despite their broad application,...
Mindfulness
2026
Manuella B Kury, Barbara L. Fredrickson, Patty van Cappellen et al.
Extensive research documents that mindfulness meditation (MM) and loving-kindness meditation (LKM) have benefits for emotional, social, and mental health outcomes. Despite this work documenting the benefits of meditation practice, research also demonstrates that meditation does not always have equivalent effects for all people. So, who is most likely to benefit from meditation practice? In this...
Frontiers in Psychiatry
2026
Aleš Oblak, Sara Rigler, Nika Kovačič et al.
Ruminations are persistent, repetitive, and often distressing thoughts centered on negative events, mood states, and psychiatric symptoms. Recognized as a maladaptive cognitive process, ruminating contributes to the onset and persistence of psychiatric disorders and is strongly linked to negative emotional states, self-criticism, and suicidality. Despite its clinical significance, a...
Journal of Neuroendocrinology
2026
Hiroe Hu, Yoojin Lee, Alaina N Tillman et al.
1 citation
Arginine vasopressin (AVP) modulates stress responsivity and social-affective behaviors, but its role in mood and trauma-related disorders remains poorly defined due to challenges in peripheral measurement. This study used copeptin, a stable, reliable, and well-validated surrogate marker of AVP secretion, to assess vasopressinergic function in a transdiagnostic sample of individuals...
Frontiers in Psychiatry
2026
Ngo Cheung
6 citations
Rapid-acting antidepressants show that mood can lift within hours when glutamatergic circuits shift from an "NMDA-dominant" to an "AMPA-dominant" state. Intravenous ketamine achieves this flip but is hampered by dissociation and logistics, while dextromethorphan + bupropion (Auvelity®) primarily supplies the initial NMDA blockade and yields slower, less durable benefit. We hypothesize that a...
General Hospital Psychiatry
2026
Gabrielle F. M. Lovell, Shreya Vasudeva, Diana Orsini et al.
Ketamine is a dissociative anesthetic with potential for treating mood, anxiety, and related disorders; however, concerns have emerged regarding hepatotoxicity in the context of chronic treatment. Systematic searches of PubMed, Scopus, and Ovid databases were conducted from inception to August 2025. Eligible studies included randomized controlled trials (RCTs), observational studies, and case...
Frontiers in Psychiatry
2026
Haihua Tian, Zongfeng Zhang, Yan He et al.
1 citation
Treatment-resistant depression (TRD) is often accompanied by persistent suicidal ideation and poor response to conventional antidepressants. Intranasal esketamine, a non-selective NMDA receptor antagonist, provides rapid antidepressant and anti-suicidal effects; transient dissociation is common, whereas ataxia-like "drunken gait" is rarely described. A 19-year-old woman with recurrent...
Chronic Stress
2026
Alexis M Klinner, David S Middlemas
Treatment-resistant juvenile depression is a globally prevalent issue, with a need for better pharmacotherapy. Typically, Selective Serotonin Reuptake Inhibitors are front line, but recently there is interest in examining using ketamine or esketamine adjunct in adolescents. In this study, a novel method is used to explore the adverse effects of sub-anesthetic doses of ketamine in a female...