Zhonghua xingwei yixue yu naokexue zazhi
May 20, 2018
YU Yongju, Peng Li, Botao Liu et al.
1 citation
Objective To investigate the relationships between mindfulness, anxiety and depression in surface warship soldiers and the mediating role of attentional control. Methods Chinese versions of State-Trait Anxiety Inventory (STAI), Center for Epidemiologic Studies Depression Scale (CES-D), Attentional Control Scale (ACS) and the Five Facet Mindfulness Questionnaire (FFMQ) were used to survey 475...
Cureus
May 18, 2018
Yasar Sattar, John M Wilson, Ali M Khan et al.
The biochemical processes involved in depression go beyond serotonin, norepinephrine, and dopamine. The N-methyl-D-aspartate (NMDA) receptor has a major role in the neurophysiology of depression. Ketamine, one of the prototypical NMDA antagonists, works rapidly in controlling depressive symptoms, including acutely suicidal behavior, by just a single injection. Ketamine may rapidly increase the...
Frontiers in Psychiatry
May 8, 2018
Ana Cecília de Menezes Galvão, Raíssa Nóbrega de Almeida, Erick Allan Dos Santos Silva et al.
102 citations
Major depression is a highly prevalent mood disorder, affecting about 350 million people, and around 30% of the patients are resistant to currently available antidepressant medications. Recent evidence from a randomized controlled trial (RCT) supports the rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression. The aim of this study was to explore the effect...
Psychiatric News
May 4, 2018
Mark Moran
If replication trials support these findings, safeguards will need to be established to guard against the risk of abuse while ensuring access to those patients who may benefit from esketamine. Intranasal esketamine appears to rapidly improve depression scores and measures of suicidality among depressed patients at imminent risk of suicide, according to a report published April 16 in AJP in...
Mindfulness
May 2, 2018
Dawn Querstret, Mark Cropley, Chris Fife-Schaw
Mindfulness interventions have been shown to be effective for health and wellbeing, and delivering mindfulness programmes online may increase accessibility and reduce waiting times and associated costs; however, research assessing the effectiveness of online interventions is lacking. We sought to: (1) assess the effects of an online mindfulness intervention on perceived stress, depression and...
International Journal of Applied Research
May 1, 2018
Kirti .
The increasing prevalence of psychological distress among adolescents and young adults has been attributed to academic pressure, family conflict, socioeconomic inequalities, trauma, excessive social media use, discrimination, and other chronic stressors. When these stressors exceed an individual's coping capacity, maladaptive coping strategies such as avoidance, rumination, substance abuse,...
Neuroscience & Biobehavioral Reviews
May 2018
Philippe Vignaud, Clément Donde, Thouraya Sadki et al.
Growing evidence has suggested that mindfulness-based interventions (MBIs) could have beneficial effects on the acute phase of depression and on the prevention of depressive relapse or recurrence. Despite growing clinical interest, the effects of MBIs on brain functioning in patients with MDD remain unclear. The aim of this systematic review was to assess the changes in brain functioning...
Journal watch
April 23, 2018
Joel Yager
Intravenous ketamine reduces symptoms of depression and suicidality for up to several weeks, but less is known about the non–FDA-approved intranasal
International Journal of Environmental Research and Public Health
April 17, 2018
Carola Rong, Caroline Park, Joshua D. Rosenblat et al.
116 citations
OBJECTIVES: Extant evidence indicates that ketamine exerts rapid antidepressant effects in treatment-resistant depressive (TRD) symptoms as a part of major depressive disorder (MDD) and bipolar disorder (BD). The identification of depressed sub-populations that are more likely to benefit from ketamine treatment remains a priority. In keeping with this view, the present narrative review aims to...
ACS Chemical Neuroscience
April 17, 2018
Lindsay P. Cameron, Charlie J. Benson, Lee E. Dunlap et al.
168 citations
Depression and anxiety disorders are debilitating diseases resulting in substantial economic costs to society. Traditional antidepressants often take weeks to months to positively affect mood and are ineffective for about 30% of the population. Alternatives, such as ketamine, a dissociative anesthetic capable of producing hallucinations, and the psychoactive tisane ayahuasca, have shown great...