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Zhonghua xingwei yixue yu naokexue zazhi

ISSN 1674-6554

2 papers in the library · publishing 2012-2017

Papers

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Effects of short term low dose melatonin and ketamine on depressive behavior and BDNF expression in rats with chronic stress depression

Zhonghua xingwei yixue yu naokexue zazhi December 20, 2017 Haonan Li, Hongwei Sun, Yanyu Wang et al.

Objective To evaluate the antidepressant action of melatonin in stress model of depression and the effects of the melatonin on depressive-like behavior. Methods Forty male Wistar rats were randomly divided into four groups(n=10): controls group (CON), chronic unpredictable mild stress group(CUS), chronic unpredictable mild stress group + melatonin group(CUS+ MT) and chronic unpredictable mild...

Role of L-arginine/nitric oxide pathway in the antidepressant effects of ketamine

Zhonghua xingwei yixue yu naokexue zazhi September 20, 2012 Guang-Fen Zhang, Nan Wang, Jinyun Shi et al.

Objective To study the role of L-arginine/nitric oxide (NO) pathway in the antidepressant effects of ketamine. Methods Forty two male Wistar rats (200-250 g) were equally randomized into 7 groups (n=6): control group (C group), L-Arginine (a precursor of NO) group (LA group), L-NAME(an non-selectivity inhibitor of NO synthase) group (LN group), ketamine 3 mg/kg group (K3 group), ketamine 10...