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Depression: all studies

Page 184 of 1,034: studies 1,831 to 1,840 of 10,336, newest first. Back to the depression overview

Research

Real world effectiveness of repeated ketamine infusions for treatment-resistant depression with comorbid borderline personality disorder.

Psychiatry Research March 5, 2023 Kevork Danayan, Noah Chisamore, Nelson B Rodrigues et al. 36 citations

Borderline personality disorder (BPD) has high rates of comorbidity with mood disorders, including treatment-resistant depression (TRD). Comorbidity of BPD with depression is associated with poorer response to antidepressants. Intravenous ketamine is a novel treatment for TRD that has not been specifically evaluated in patients with comorbid BPD. In this retrospective analysis of data collected...

TOLERANCE AND ACCEPTABILITY OF INTRAVENOUS KETAMINE THERAPY FOR TREATMENT RESISTANT DEPRESSION: A MIXED METHODS ASSESSMENT

Journal of Pakistan Psychiatric Society March 3, 2023 Sawera Mansoor, Khalid Hayat Khan, Manzoor Ahmed Faridi 3 citations

Objectives: This study was conducted to evaluate the response of treatment resistant depression to IV ketamine therapy protocol and explore the perspectives of patients regarding the acceptability of this treatment modality. Study Design: Mixed methods assessment including Quasi experimental design and Qualitative interviews. Place and Duration of Study: The study was conducted at Department of...

Effect of mindfulness on anxiety and depression in insomnia patients: A systematic review and meta-analysis

Frontiers in Psychiatry March 2, 2023 Hangyu Li, Wanli Qin, Nannan Li et al.

BackgroundAs a common clinical symptom, insomnia has a high incidence of combined mental illness and it is also a risk factor for the development of depression, anxiety and suicide. As a new concept in the field of health in recent years, mindfulness therapy can improve insomnia, anxiety and depression, which is a new way to solve such diseases.ObjectiveThis study aims to systematically...

Mental Health during fatherhoood. Biopsychosocial aspects and questionnaire for depression PHQ9

European Psychiatry March 1, 2023 Pierre A Geoffroy, Rodolphe Borand, Marine Ambar Akkaoui et al.

Introduction Sleep and circadian markers are of increasingly growing interest to help better predicting suicide. Indeed, specific sleep disorders and circadian rhythm disorders have been associated to suicidal behaviors, and the most replicated findings are insomnia and nightmares. Nevertheless, these interesting preliminary studies did not examine the chronology and trajectories of these dream...

Systematic Review on the Mechanisms of Action of Psilocybin in the Treatment of Depression

European Psychiatry March 1, 2023 M. C. Q. Lin, H. Lee, V.-W.-L. Tsang et al.

Introduction Despite emerging evidence suggesting the efficacy of psilocybin in the treatment of mood disorders such as depression, the exact mechanisms by which psilocybin is able to elicit these antidepressant effects remains unknown. Objectives As the use of psilocybin as a treatment modality for depression has garnered increasing interest, this study aims to summarize the existing evidence...

Mentation processes such as excessive mind wandering, rumination, and mindfulness mediate the relationship between ADHD symptoms and anxiety and depression in adults with ADHD

European Psychiatry March 1, 2023 Ali Kandeğer, Şerife Odabaş Ünal, M. T. Ergün

Introduction: Excessive mind wandering is a common feature of ADHD in adulthood also referred to as mental restlessness and ceaseless mental overactivity. ADHD is a predisposing factor for many psychiatric symptoms, especially negative emotions such as depression and anxiety. Rumination is thought to be a mediator for depression in individuals with ADHD. The above-mentioned mental processes may...

Mindfulness for depression management in men with prostate cancer

JAAPA March 1, 2023 Amber Teigen

ABSTRACT: Increasing incidence and survival rates of prostate cancer are leaving more men to suffer the sequelae of their diagnosis and treatment, like depression. Depression and other negative psychosocial factors significantly affect this population but often go undiagnosed and/or ineffectively managed. This case report focuses on the negative effects of prostate cancer diagnosis and...

Cortical inhibition function is associated with baseline suicidal symptoms and post-ketamine suicidal symptom reduction among patients with treatment-resistant depression and strong suicidal ideation.

Journal of Psychiatric Research March 1, 2023 Mu-Hong Chen, T. Su, Li-Fen Chen et al.

BACKGROUND Whether cortical excitation and inhibition functions differ between patients with treatment-resistant depression (TRD) and strong suicidal ideation (SI) and healthy subjects and whether 0.5 mg/kg ketamine infusion can modulate cortical excitation and inhibition functions among patients with TRD-SI remain unclear. METHODS A total of 29 patients with TRD-SI and 35 age- and sex-matched...

Adjunctive short- and long-term combination treatment of esketamine and VNS in difficult to treat depression (DTD)

European Psychiatry March 1, 2023 Erhan Kavakbasi, Bernhard T Baune

IntroductionNMDA-Receptor antagonists have rapid antidepressant and antisuicidal properties. However, the antidepressant effect is short lasting raising the question of best maintenance strategy, which is unanswered so far. Invasive vagus nerve stimulation (VNS) as a treatment option for refractory and chronic major depression was shown to reduce the need of maintenance treatment sessions in...

Effect of pre-administration of esketamine intraoperatively on postpartum depression after cesarean section: A randomized, double-blinded controlled trial.

Medicine March 1, 2023 Wei Wang, Bin Ling, Qian Chen et al.

Background: To evaluate the effect of pre-administration of esketamine intraoperatively on the occurrence of postpartum depression after cesarean section under combined spinal-epidural anesthesia. Methods: A total of 120 women aged 24 to 36 years undergoing cesarean section by spinal-epidural anesthesia with American Society of Anesthesiologists physical status II were enrolled. According to...

DOI: 10.1097/md.0000000000033086 (opens in new tab) Full text (opens in new tab) Ketamine Humans Depression, postpartum Anesthesia, epidural +4