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Cannabis for addiction: all studies

Page 5 of 9: studies 41 to 50 of 88, newest first. Back to the cannabis for addiction overview

Research

Policy in focus: Is psilocybin the next cannabis?

Canadian Medical Association Journal November 14, 2021 Greg Basky 7 citations

Research interest in the therapeutic use of psilocybin, or "magic mushrooms," is growing alongside a "wild west" of dispensaries in Canada and the United States. The past decade has seen a revival of research exploring the clinical use of psychedelics in treating depression, addiction,

Δ 9-Tetrahydrocannabinol During Adolescence Reprograms the Nucleus Accumbens Transcriptome, Affecting Reward Processing, Impulsivity, and Specific Aspects of Cocaine Addiction-Like Behavior in a Sex-Dependent Manner.

The International Journal of Neuropsychopharmacology November 12, 2021 Javier Orihuel, Roberto Capellán, David Roura-Martínez et al.

Cannabis exposure during adolescence is associated with emotional and motivational alterations that may entail an enhanced risk of developing psychiatric disorders. In rodent models, exposure to cannabinoids during adolescence leads to increased self-administration of opiates and cocaine, however, the psychological and neural mechanisms and the sex-specificity of this phenomenon are largely...

Psilocybin: Next to treat depression, OCD and nicotine addiction

Alcoholism & Drug Abuse Weekly September 24, 2021 Alison Knopf

First it was the plant, cannabis. How could this be made into a saleable profit‐making commodity when it grows in the ground? Witness the marijuana (a chemical from the plant) industry, which lobbied to make sure laws in states that legalized it banned people from growing more than a few plants.

Cannabis Use and Psychosis – Modern Views on the Problem. Narrative Synthesis

Medicina 2021 A. J. Kolgashkin, П. Н. Николаев, E. J. Tetenova et al. 1 citation

Cannabis continues to be the most widely used drug worldwide. Recently, there has been two trends in the field: a liberalization of cannabis-related legislation in a number of countries, as well as an increase in the content of the psychoactive component in cannabis plant – tetrahydrocannabinol. The review covers a topic that has been little studied in Russian addiction science – cannabis use...

The good, the bad, and the intoxicated

2021 Natasha Leigh Mason

Cannabis is the most commonly used illicit drug and is known to alter state of consciousness and impair neurocognitive function. However, the mechanisms underlying these effects have yet to be fully elucidated. Rodent studies suggest that 9-tetrahydrocannabinol (THC) activates dopaminergic neurons in the limbic system, subsequently enhancing dopamine, which is implicated in the rewarding...

Individual and combined effects of Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) on striato-cortical connectivity in the human brain

bioRxiv (Cold Spring Harbor Laboratory) November 21, 2020 Matthew B. Wall, Tom P. Freeman, Chandni Hindocha et al. 4 citations preprint

Abstract Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are two major constituents of cannabis with contrasting mechanisms of action. THC is the major psychoactive, addiction-promoting, and psychotomimetic compound, while CBD may have somewhat opposite effects. The brain effects of these drugs alone and in combination are poorly understood. In particular the striatum is implicated in the...

MDMA Use by Paris Medical Students: Prevalence and Characteristics

Substance Use & Misuse October 24, 2020 Balthazar Bazin, David Duroy, Michel Lejoyeux 27 citations

3,4-Methylenedioxy-N-methylamphetamine (MDMA) is increasing being used by youth in Europe and in France, but characteristics of its use are unknown. Objectives: The aim was to characterize MDMA use in a sample of French medical students. Methods: Cross-sectional study of Paris VII medical students (N = 592) with an online self-reporting questionnaire. Results: 592 students completed the online...

Risk factors for the onset of dependence and chronic psychosis due to cannabis use: Survey of patients with cannabis‐related psychiatric disorders

Neuropsychopharmacology Reports September 7, 2020 Toshihiko Matsumoto, Toshitaka Kawabata, Kyoji Okita et al. 9 citations

AIM: The objective of the current study was to identify risk factors that affect the onset of dependence and chronic psychosis due to cannabis use. METHODS: We examined clinical genetic factors, psychiatric disorders prior to cannabis use, starting age of cannabis use, duration and frequency of cannabis use, types of cannabis products used, combined use of other psychoactive substances, and the...

Evidence That Cannabis Exposure, Abuse, and Dependence Are Related to Glutamate Metabolism and Glial Function in the Anterior Cingulate Cortex: A 1H-Magnetic Resonance Spectroscopy Study

Frontiers in Psychiatry August 20, 2020 Jeremy J. Watts, Ranjini Garani Ramesh, Tânia Maria Sarmento Silva et al. 21 citations

There is evidence that long-term cannabis use is associated with alterations to glutamate neurotransmission and glial function. In this study, twenty-six long-term cannabis users (males=65.4%) and 47 non-cannabis using healthy controls (males=44.6%) underwent proton magnetic resonance spectroscopy (1H-MRS) of the anterior cingulate cortex (ACC) in order to characterize neurometabolite...

DOI: 10.3389/fpsyt.2020.00764 (opens in new tab) Cannabis Glutamate receptor Glutamine Anterior cingulate cortex +4

Who Turns to Amazonian Medicine for Treatment of Substance Use Disorder? Patient Characteristics at the Takiwasi Addiction Treatment Center

Journal of Studies on Alcohol and Drugs July 1, 2020 Ilana Berlowitz, Heinrich Walt, Christian Ghasarian et al. 19 citations

Our results suggest that the Amazonian medicine-based therapy attracts a diverse patient group not limited to regional residents and may be particularly appealing to more impaired SUD patients with a history of unsuccessful treatment. The sample's cultural diversity suggests an existing interest in such therapies among international SUD treatment-seeking patients. These findings are relevant in...