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Canadian Medical Association Journal

ISSN 0820-3946, 1488-2329

8 papers in the library · 253 citations · publishing 2007-2025

Papers

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Mortality risk among people receiving acute hospital care for hallucinogen use compared with the general population.

Canadian Medical Association Journal March 2, 2025 Daniel T. Myran, Jennifer Xiao, Nicholas Fabiano et al. 8 citations

Background: Although clinical trials involving psychedelic-assisted psychotherapy have not observed short-term increases in the risk of death, limited data exist on mortality associated with hallucinogen use outside of controlled trial settings. We sought to determine whether people with an emergency department visit or hospital admission involving hallucinogen use were at increased risk of...

DOI: 10.1503/cmaj.241191 (opens in new tab) Full text (opens in new tab) Hallucinogen use Psychedelic use Substance use Drug use +21

Diagnosis and management of toxicity associated with the recreational use of nitrous oxide

Canadian Medical Association Journal August 20, 2023 Cyrille de Halleux, D. Juurlink

CMAJ | August 21, 2023 | Volume 195 | Issue 32 E1075 Nitrous oxide (N2O) has become a popular but dangerous recreational drug. Colloquially referred to as “laughing gas,” it was first used therapeutically in 1844 for patients undergoing dental surgery.1 Although a weak anesthetic, it remains in use today, especially for pediatric and dental procedures.2 Its recreational use is now recognized as...

High time? Psychedelics on cannabis-like fast track to legalization

Canadian Medical Association Journal December 18, 2022 Kevin Zannese 9 citations

Alberta will soon become the first province to regulate psychedelic-assisted therapy. But, as with cannabis, momentum for medical access to psychedelics is outpacing research to guide their use. Earlier this year, Health Canada amended its Special Access Program to allow physicians to request

Policy in focus: Is psilocybin the next cannabis?

Canadian Medical Association Journal November 14, 2021 Greg Basky 7 citations

Research interest in the therapeutic use of psilocybin, or "magic mushrooms," is growing alongside a "wild west" of dispensaries in Canada and the United States. The past decade has seen a revival of research exploring the clinical use of psychedelics in treating depression, addiction,

Psychedelic and nonpsychedelic LSD and psilocybin for cluster headache

Canadian Medical Association Journal February 16, 2016 Wm. Jeptha Davenport 14 citations

Tupper and colleagues highlight reasons for renewed interest in the use of psychedelic drugs as adjuncts to psychotherapy.[1][1] Clinicians have an interest in extending research into headache medicine, especially the treatment of cluster headaches (prevalence roughly 0.1%) when episodes are

DOI: 10.1503/cmaj.1150082 (opens in new tab) Full text (opens in new tab) Psilocybin Cluster headache Headaches Alternative medicine +1

Psychedelic medicine: a re-emerging therapeutic paradigm

Canadian Medical Association Journal September 8, 2015 Kenneth W. Tupper, Evan Wood, Richard Yensen et al. 189 citations

In clinical research settings around the world, renewed investigations are taking place on the use of psychedelic substances for treating illnesses such as addiction, depression, anxiety and posttraumatic stress disorder (PTSD). Since the termination of a period of research from the 1950s to the

LSD: a new treatment emerging from the past

Canadian Medical Association Journal August 4, 2015 Erika Dyck 25 citations

Psychedelics fell from medical grace nearly half a century ago, but recent activity suggests that some researchers have "high hopes" for their return.[1][1],[2][2] Over 60 years ago, Albert Hofmann at Sandoz Pharmaceutical Laboratories in Switzerland first synthesized lysergic acid diethylamide