O presente estudo tem como objetivo analisar os efeitos terapêuticos da ayahuasca na saúde mental por meio de uma revisão integrativa. Para isso, foram levantados artigos publicados nos últimos dez anos nas bases de dados PubMed, Scopus e Google Acadêmico, utilizando os descritores “ayahuasca”, “depressão”, “ansiedade” e “saúde mental”. Após o exame dos 96 trabalhos capturados, 18 estudos...
Background: While psychedelics are often claimed to enhance creativity, their precise effects on distinct stages of creative cognition remain poorly understood. This study investigated the acute effects of an ayahuasca-inspired formulation combining N,N-dimethyltryptamine (DMT) and harmine (DMT/HAR), as well as harmine alone (HAR), on micro-level (divergent/convergent thinking) and macro-level...
While psychedelics are often claimed to enhance creativity, their precise effects on distinct stages of creative cognition remain poorly understood. This study investigated the acute effects of an ayahuasca-inspired formulation combining N,N-dimethyltryptamine (DMT) and harmine (DMT/HAR), as well as harmine alone (HAR), on micro-level (divergent/convergent thinking) and macro-level (creative...
CIENCIAMATRIAAugust 1, 2025Daniel Santiago Rivera-Rosero, Tannia Cristina Poveda-Morales
El objetivo de la presente investigación fue realizar un estudio de la bebida ancestral ayahuasca (Banisteriopsis CAAPI) para la elaboración de un menú gastronómico. La metodología investigativa descriptiva y explicativa, mediante los métodos analítico sintético, histórico lógico, y análisis documental. Los resultados y análisis realizados y los alimentos elaborados, queda en constancia el...
Ayahuasca is a traditional Amazonian brew composed primarily of Banisteriopsis caapi and Psychotria viridis, drawing increasing interest for its psychedelic effects and potential therapeutic applications. Its pharmacological action is based on the synergistic combination of β-carbolines (harmine, tetrahydroharmine, and harmaline), which act as reversible inhibitors of monoamine oxidase A...
Abstract Ayahuasca is a psychedelic brew used for centuries in religious rituals by indigenous cultures. Recent studies suggest its potential to reduce depression and anxiety and as an alternative for treating ethanol and tobacco use disorders. However, research on its impact on cocaine use disorder remains limited. We investigated the effects of ayahuasca on the reinstatement of...
Pain is a protective mechanism that can be classified into acute and chronic types. Ayahuasca is a psychoactive brew rich in dimethyltryptamine or DMT (a 5-HT2A receptor agonist), and harmine (a monoamine-oxidase (MAO) inhibitor) used for religious and therapeutic purposes. Previous preclinical and anecdotal evidence suggests that ayahuasca and its compounds have antinociceptive and...
Depression is a common disorder around the world, according to the WHO (World Health Organization) about 350 million people worldwide suffer from the disease, a number that is growing every day. Brazil is the second country in the Americas with the highest number of depressive people, where about 5.8% of the population has been diagnosed with the pathology. Depression is a chronic and recurrent...
Este texto tem como propósito compartilhar uma trajetória pessoal do que tem sido uma jornada de aprofundamento espiritual que começou quando participei, pela primeira vez, de uma cerimônia com ayahuasca, em 2015. Isso lançou o autoconhecimento como uma necessidade urgente em mim, em vez das angústias existenciais que permeavam minha vida. Desde então, o uso ritual da ayahuasca tornou-se uma...
PsychoactivesJune 25, 2025Guillermo Escobar-Cornejo, Fernando P. Cárdenas, Diego Torres et al.
Objective: To provide a state of the art on the use, role, and function of music during psychedelic-assisted therapy (PAT) with ayahuasca. Introduction: Ayahuasca is a medicinal brew with psychoactive qualities used by indigenous communities throughout the Amazon region, and music is deemed crucial during ayahuasca experiences. In PAT, music forms part of the set and setting, but it lacks...