Os transtornos psiquiátricos representam importante problema de saúde pública mundial, frequentemente associados a elevada morbidade, incapacidade funcional e impacto significativo na qualidade de vida. Apesar dos avanços terapêuticos disponíveis, muitos pacientes permanecem refratários aos tratamentos convencionais, estimulando a busca por novas abordagens terapêuticas. Nesse contexto, os...
PsychedelicsMay 30, 2026Vinicius Ryu Kami, Beatriz Borges Bueno Salle, Giovanni Porto et al.
Background Contemporary psychiatry is associated with several challenges, including limited remission rates in complex and severe psychiatric disorders. In this context, psychedelics have re-emerged globally as a promising therapeutic paradigm. Brazil occupies a unique position in this scenario, mainly due to the legal protection and cultural integration of Ayahuasca, which fosters a distinct...
Abstract The visionary beverage known as ayawaska ( yage, oni , caapi , camaranti , etc.) among the Indigenous Nations of the Amazon has, over the past century, generated increasing academic interest and popular fascination, leading to a boom in psychedelic tourism and “neo-shamanism”. This article attempts to account for the uses of ayawaska within the contemporary cultural context of the...
This chapter is designed to offer a comprehensive overview of five core psychedelic medicines—ketamine, psilocybin, MDMA, LSD, and ayahuasca—highlighting their distinct pharmacological properties, cultural origins, therapeutic applications, and clinical research. Although each substance offers a unique entry point into expanded states of consciousness, they share a common potential to catalyze...
This chapter examines the essential role of personal experience in psychedelic therapy, through a raw and reflective account of the author’s first Ayahuasca ceremony. It illustrates how direct experience with psychedelics can become a profound source of clinical wisdom over time. Drawing on Bateson’s systemic theories and the Taoist concept of “no-mind,” the author explores how psychedelic...
O conjunto de textos reúne reflexões e narrativas a partir da experiência e da cosmovisão do povo Kanamari, articulando identidade indígena, saberes ancestrais, espiritualidade, arte e resistência frente às múltiplas formas de colonialidade ainda vigentes. A trajetória do artista indígena Jaime Riveros é apresentada como símbolo da luta contra o racismo estrutural e a marginalização nos...
ULAKES JOURNAL OF MEDICINEMay 13, 2026Maria Eduarda Marquezi Machioni, Giulia Argueles de Oliveira, Ana Luísa da Silva Rueda et al.
Diante da crescente prevalência dos diagnósticos de transtornos ansiosos no Brasil e no mundo, o presente artigo visa analisar as contribuições das substâncias psicodélicas no tratamento dos transtornos. Por meio de uma revisão narrativa, foram examinados estudos sobre o potencial terapêutico de compostos como LSD, psilocibina, ayahuasca e MDMA. Os resultados colhidos apontam que essas...
Mangoni, V. & Robledo, L. (Directors). Compuesto, Alexandra ‘Sasha’ (Producer). 2020. The Song that Calls You Home. Good Docs. 72 mins. The Song That Calls You Home is an informative documentary on plant medicine that focuses on the perceived therapeutic properties of ayahuasca. The film presents itself as an exploration of this psychedelic plant as a pathway to healing and self-discovery. Its...
Psilocybe mushrooms (psilocybin/psilocin [PSI/PSC]) and ayahuasca (N,N-dimethyltryptamine [DMT]) are hallucinogenic serotonergic agonists. Pregnant and lactating women are frequently omitted from clinical studies; hence minimal developmental/reproductive/neurotoxicity (DART/DNT) and endocrine disruption (ED) data in humans are available. Hallucinogens contaminated with pesticides may have...
Terceira MargemApril 25, 2026Henrique de Oliveira Lee, Waldenis Pereira da Trindade Júnior
Este artigo propõe uma leitura da liturgia do Santo Daime a partir da noção de “formação cultural de compromisso”, conceito inspirado em Carlo Ginzburg e Sigmund Freud. Analisa-se o processo histórico e sincrético que deu origem a essa religião brasileira, situando-a no contexto das traduções culturais entre saberes indígenas e o catolicismo popular. A partir de uma genealogia do uso da...