August 14, 2017
S. Maddali-Bongi
Mindfulness meditation is a mental technique which cultivates attentional focus and stability by directing the mind to remain connected to the present experience, moment by moment. Scientific literature in healthy subjects have correlated mindfulness training to improvements in stress, anxiety and depressed mood. Moreover, basing on evidence we can state that mindfulness may have an important...
Sleep and Hypnosis
August 14, 2017
Javed Ather Siddiqui, Shazia Farheen Qureshi, Abdul Khaliq Al Ghamdi
3 citations
Sleep paralysis (SP) is a benign, transient episode of immobility lasting a few seconds to a few minutes that can occur while falling asleep or on awakening.It is a condition of unknown etiology.During the episode, all the skeletal muscles are virtually 'paralyzed', resulting in an inability to move or speak but individual remains conscious.Because it occurs in a clear sensorium, the individual...
Frontiers in Psychiatry
August 13, 2017
Luisa Ponzoni, Daniela Braida, Gianpietro Bondiolotti et al.
9 citations
3,4-methylenedioxymethamphetamine (MDMA) and its derivatives, 2,5-dimethoxy-4-bromo-amphetamine hydrobromide (DOB) and para-methoxyamphetamine (PMA) are recreational drugs whose pharmacological effects have recently been attributed to serotonin 5HT2A/C receptors. However, there is growing evidence that the oxytocin/vasopressin system can modulate some the effects of MDMA. In this study, MDMA...
Frontiers in Psychology
August 8, 2017
Marcelo Demarzo, Jesus Montero-Marin, Marta Puebla-Guedea et al.
123 citations
Background Many attempts have been made to abbreviate mindfulness programmes in order to make them more accessible for general and clinical populations while maintaining their therapeutic components and efficacy. The aim of this study was to assess the efficacy of an 8-week mindfulness-based intervention (MBI) programme and a 4-week abbreviated version for the improvement of well-being in a...
Complementary Therapies in Clinical Practice
August 2017
Carlin J. Miller, Brianne Brooker
Parents and teachers of children with attention-deficit/hyperactivity disorder (ADHD) are at-risk for a range of suboptimal psychosocial outcomes, including mental health difficulties and heightened stress, problems perhaps ameliorated through mindfulness-based programming. To show pilot data from an investigation of the outcomes of a purpose-built mindfulness training for parents and teachers...
L'Encephale
August 2017
B Romeo, W Choucha, P Fossati et al.
The aim of this review was to determine the clinical and biological predictors of the ketamine response. A systematic research on PubMed and PsycINFO database was performed without limits on year of publication. The main predictive factors of ketamine response, which were found in different studies, were (i) a family history of alcohol dependence, (ii) unipolar depressive disorder, and (iii)...
Psycho-Oncology
August 2017
David Victorson, Vered Hankin, James Burns et al.
In a pilot randomized controlled trial, examine the feasibility and preliminary efficacy of an 8-week, mindfulness training program (Mindfulness Based Stress Reduction) in a sample of men on active surveillance on important psychological outcomes including prostate cancer anxiety, uncertainty intolerance and posttraumatic growth. Men were randomized to either mindfulness (n = 24) or an...
Psychopharmacology
August 1, 2017
Amy W M Ewald, Peter J Bosch, Aimee Culverhouse et al.
Kappa-opioid receptor (KOPr) agonists have pre-clinical anti-cocaine and analgesic effects. However, side effects including sedation, dysphoria, aversion, anxiety and depression limit their therapeutic development. The unique structure of salvinorin A has been used to develop longer acting KOPr agonists. We evaluate two novel C-2 analogues of salvinorin A, ethoxymethyl ether Sal B (EOM Sal B)...
Journal of Natural Products
July 28, 2017
Anil Yilmaz, Rachel Saylor Crowley, Alexander M. Sherwood et al.
Columbin (1) is a furanolactone diterpene isolated from the roots of Jateorhiza and Tinospora species. These species generally grow in Asia and Africa and have been used in folk medicine for their apparent analgesic and antipyretic activities. Columbin (1) is of particular interest due to its structural similarity to the known kappa-opioid receptor (KOR) agonist salvinorin A. Given that the KOR...
Clinical and translational gastroenterology
July 27, 2017
Jasmohan S Bajaj, Michael Ellwood, Timothy Ainger et al.
Patient-reported outcomes such as health-related quality of life (HRQOL) are impaired in cirrhosis due to under-treated mood and sleep disorders, which can adversely impact their caregivers. Mindfulness-based stress reduction (MBSR) can improve patient-reported outcomes (PRO) in non-cirrhotic patients but their impact in cirrhosis is unclear. To evaluate the effect of MBSR and supportive group...