Psychological Medicine
March 5, 2018
Sagnik Bhattacharyya, Thomas T. J. Sainsbury, Paul Allen et al.
16 citations
BACKGROUND: Cannabis and its main psychoactive ingredient δ-9-tetrahydrocannibidiol (THC) can induce transient psychotic symptoms in healthy individuals and exacerbate them in those with established psychosis. However, not everyone experience these effects, suggesting that certain individuals are particularly susceptible. The neural basis of this sensitivity to the psychotomimetic effects of...
Research in Gerontological Nursing
March 2, 2018
Christine R. Kovach, Crystal-Rae Evans, Lisa Sattell et al.
35 citations
Mindfulness interventions have been beneficial for healthy adults and individuals experiencing a stressful medical or mental health diagnosis. The purposes of the current study were to: (a) determine feasibility of mindfulness for older adults in long-term residential settings, and (b) examine differences in outcomes between a mindfulness and cognitive activity. The current study is the first...
Annals of family medicine
March 1, 2018
Samuel Y S Wong, Yu Ying Sun, Aaroy T Y Chan et al.
Purpose: We undertook a randomized controlled trial to assess the efficacy of group-based behavioral activation with mindfulness (BAM) for treating subthreshold depression in primary care in Hong Kong. Methods: We recruited adult patients aged 18 years or older with subthreshold depression from public primary care clinics and randomly assigned them to a BAM intervention group or a usual care...
Journal of Clinical Psychology
March 2018
Tim Lomas, Juan Carlos Medina, Itai Ivtzan et al.
Among efforts to improve the well-being of healthcare professionals are initiatives based around mindfulness meditation. To understand the value of such initiatives, we conducted a systematic review of empirical studies pertaining to mindfulness in healthcare professionals. Databases were reviewed from the start of records to January 2016. Eligibility criteria included empirical analyses of...
Kidney research and clinical practice
March 2018
Bo Kyung Sohn, Yun Kyu Oh, Jung-Seok Choi et al.
Many patients with end-stage renal disease (ESRD) undergoing hemodialysis (HD) experience depression. Depression influences patient quality of life (QOL), dialysis compliance, and medical comorbidity. We developed and applied a group cognitive behavioral therapy (CBT) program including mindfulness meditation for ESRD patients undergoing HD, and measured changes in QOL, mood, anxiety, perceived...
Hippocampus
March 2018
Boris Mlinar, Renato Corradetti
The hippocampus is functionally differentiated along its longitudinal axis, with the dorsal and ventral segments preferentially involved in cognitive and emotional processing, respectively. Serotonergic modulation of hippocampal function has been extensively studied, but its relation to the dorsoventral axis has remained largely unknown. To examine the modulation of hippocampal output along the...
Postgraduate medicine
March 2018
Meghan K. Edwards, Paul D Loprinzi
No review papers have examined studies that have directly compared non-active forms of meditation with exercise to evaluate effects on physical or psychosocial outcomes, which was the purpose of this paper. Studies were included if they had a randomized controlled trial (RCT) design, included a non-active form of meditation and exercise as intervention arms, and evaluated physical or...
SHILAP Revista de lepidopterología
March 1, 2018
Elaheh Mahmoudi, Mehrdad Faizi, Reza Hajiaghaee et al.
14 citations
Background and objectives: Considering the increasing prevalence of depression, many studies are launched to investigate new antidepressant treatments. The present research has shown how psilocybin as an active compound of Psilocybe cubensis (Earle) Singer extract (PCE) can change the parameters related to depression and anxiety in animal models. Both serotonin (5-hydroxytryptamine: 5-HT) and...
Revista Brasileira de Psiquiatria
February 24, 2018
Camila Bernardes, P. Mattos, B. P. Nazar
Rev Bras Psiquiatr. 2018;40:110 Brazilian Journal of Psychiatry 00000000-0002-7316-1185 | doi:10.1590/1516-4446-2017-2380 Singh et al. reported that two or three weekly 40 min i.v. infusions of ketamine (0.5 mg/kg) are safe and effective for maintaining an acute response to ketamine during one month of treatment for resistant depression (TRD). We present herein the results of an open label...
Neuropharmacology
February 21, 2018
Sean J Belouin, Jack E Henningfield
189 citations
The purpose of this commentary is to provide an introduction to this special issue of Neuropharmacology with a historical perspective of psychedelic drug research, their use in psychiatric disorders, research-restricting regulatory controls, and their recent emergence as potential breakthrough therapies for several brain-related disorders. It begins with the discovery of lysergic acid...