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Thomas T. J. Sainsbury

1 paper in the library · 16 citations · publishing 2018

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Increased hippocampal engagement during learning as a marker of sensitivity to psychotomimetic effects ofδ-9-THC

Psychological Medicine March 5, 2018 Sagnik Bhattacharyya, Thomas T. J. Sainsbury, Paul Allen et al. 16 citations

BACKGROUND: Cannabis and its main psychoactive ingredient δ-9-tetrahydrocannibidiol (THC) can induce transient psychotic symptoms in healthy individuals and exacerbate them in those with established psychosis. However, not everyone experience these effects, suggesting that certain individuals are particularly susceptible. The neural basis of this sensitivity to the psychotomimetic effects of...