In this paper I explore health and illness through the lens of enactivism, which is understood and developed as a bodily-based worldly-engaged phenomenology. Various health theories - biomedical, ability-based, biopsychosocial - are introduced and scrutinized from the point of view of enactivism and phenomenology. Health is ultimately argued to consist in a central world-disclosing aspect of...
A symptom cluster is very common among oncological patients: cancer-related fatigue (CRF), emotional distress, sleep difficulties, pain, and cognitive difficulties. Clinical applications of interventions based on non-ordinary states of consciousness, mostly hypnosis and meditation, are starting to be investigated in oncology settings. They revealed encouraging results in terms of improvements...
La ayahuasca es una bebida psicoactiva compuesta por dos plantas que tienen su crecimiento en la selva amazónica (Banisteriopssis caapi o yagé y Psychotria viridis o chacruna).Esta última contiene el principio psicoactivo DMT, causante de intensas alucinaciones. Se presenta el caso de un varón de 33 años de nacionalidad británica que acude al servicio de urgencias psiquiátricas por alteraciones...
Recent clinical trials indicate favorable therapeutic outcomes of psychedelic-assisted psychotherapy for anxiety and treatment-resistant depression. Whereas the neurobiological systems underlying these effects are not well understood, animal behavioral models can serve to investigate these mechanisms. For the current study, we implemented 2 rodent models predictive of anxiolytic drug effects, a...
Rapid antidepressant effects of S-ketamine have repeatedly been confirmed in patients with depression, as well as in chronic unpredictable mild stress (CUMS) animal models. However, the pharmacological study of S-ketamine for anti-postpartum depression has not been considered. In this study, the classical method of reproductive hormone withdrawal was used to construct a rat model of postpartum...
INTRODUÇÃO: A ayahuasca é uma bebida preparada utilizando-se a casca do cipó Banisteriopsis caapi junto com as folhas de Psychotria viridis, apresentando o alcaloide dimetiltriptamina (DMT), responsável pela ativação do receptor serotoninérgico, e as β-carbolinas harmina e harmalina, as quais possuem função de inibição da enzima monoaminoxidase. O decocto, que é tradicionalmente utilizado em...
Revista Virtual de Química2022João Pedro Evangelista Ferreira, Stella Bortoli, Airton Vicente Pereira1 citation
Depression and anxiety disorders are a major challenge for modern psychiatry, especially when shown to be resistant to conventional means of treatment. Over the past decade, psychedelic and entactogen substances, once stigmatized, have regained an ever-growing momentum as potential therapeutic agents for these disorders. The present study offers a review and comparison of the pharmacological...
The article is devoted to the analysis of present-day international cooperation in the field of science, innovation and medicine. Using the example of the work of the Multidisciplinary Association for Psychedelic Science abroad, namely in Switzerland, Mexico and Israel, the author considers a completely new area of “diplomacy for science” — the cooperation in the study of illicit substances....
3,4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) for post-traumatic stress disorder (PTSD) has demonstrated promise in multiple clinical trials. MDMA is hypothesized to facilitate the therapeutic process, in part, by decreasing fear response during fear memory processing while increasing extinction learning. The acute administration of MDMA in healthy controls modifies recruitment...
During the 2020 COVID-19 epidemic a variety of social activities migrated online, including religious ceremonies and rituals. One such instance is the case of Santo Daime, a Brazilian rainforest religion that utilizes the hallucinogenic brew ayahuasca in its rituals. During the pandemic, multiple Santo Daime rituals involving the consumption of ayahuasca took place online, mediated through Zoom...