Depression and anxiety disorders are a major challenge for modern psychiatry, especially when shown to be resistant to conventional means of treatment. Over the past decade, psychedelic and entactogen substances, once stigmatized, have regained an ever-growing momentum as potential therapeutic agents for these disorders. The present study offers a review and comparison of the pharmacological...
Most of the new developed drugs are natural or analogous products, including those that act on the Central Nervous System. The search for new drugs for the treatment of depression is increasing, in view of the high worldwide incidence of this mental disorder. In this context, tryptophan derivatives have an antidepressant effect due to the presence of indole rings, which give them a similarity...