agonists containing substances emerging on the illicit drug market as a replacement for N,N-diethyllysergamide (LSD). Despite the increasing use of NBOMes for diagnostic, research and recreational purposes, only a limited number of studies have focussed on their in vivo effect. Here, we investigated pharmacokinetics, systemic toxicity, thermoregulation in individually and group-housed animals,...
To investigate if clinical features associated with acute cannabis intoxication in patients presenting to Emergency Departments for medical assistance differ according to patient age and sex. We analysed presentations in the Euro-DEN Plus dataset from 2014 to 2019 in which cannabis was the only drug involved (except for alcohol), and age, sex and alcohol co-ingestion had been recorded. Age was...
A sharp increase in the prevalence of neuropsychiatric disorders, including major depression, anxiety, substance use disorders and posttraumatic stress disorder (PTSD) has occurred due to the traumatic nature of the persisting COVID-19 global pandemic. PTSD is estimated to occur in up to 25% of individuals following exposure to acute or chronic trauma, and the pandemic has inflicted both forms...
oURspaceAugust 1, 2022Caeleigh Ann O'Sullivan Landry
Background. Public safety personnel (PSP) are at an increased risk for developing mental disorders compared to the general population. The PSP Wellbeing Course is a transdiagnostic internet-delivered cognitive behaviour therapy (ICBT) course tailored to assist PSP to manage symptoms of depression, anxiety, and posttraumatic stress injuries using cognitive behavioural strategies. While the...
ExploreAugust 1, 2022Jingni Ma, Dongrong Zhao, Naihong Xu et al.
OBJECTIVE In recent years, digital techniques, such as virtual reality (VR) has been employed in tandem with more traditional psychological interventions. The aim of this study is to investigate whether VR-based mindfulness training can improve mental health outcomes, and notably mindfulness levels amongst adults. In addition, this review seeks to summarise the various designed VR scenarios, as...
ABSTRACT Anxiety is a feeling of uneasiness, worry, fear that is uncertain and can be triggered by unknown things or new experiences. Intervention in anxiety can be done with MBCT (Mindfulness-Based Cognitive Therapy). This therapy combines cognitive behavioral techniques with mindfulness strategies to help individuals better understand and manage their thoughts and emotions to achieve relief...
Abstract Objectives Mindfulness training has been theorised to have beneficial effects on mental health through initially changes in attention mechanisms. The aim of the present study was to assess the impact of a short mindfulness meditation on the P300 event-related potential (ERP), a neural marker of attention, in meditation-naïve participants. Methods As mindfulness practice is based on...
Background: Over the last two decades, a number of studies have highlighted the potential of psychedelic therapy. However, questions remain to what extend these results translate to naturalistic samples, and how contextual factors and the acute psychedelic experience relate to improvements in affective symptoms following psychedelic experiences outside labs/clinics. The present study sought to...
Abstract The Western world is experiencing a resurgence of interest in the therapeutic potential of psychedelics, most of which are derived from plants or fungi with a history of Indigenous ceremonial use. Recent research has revealed that psychedelic compounds have the potential to address treatment‐resistant depression and anxiety, as well as post‐traumatic stress disorder and addictions....
BackgroundYoga practices, including breathing, meditation, and posture protocols (asanas), have been shown to facilitate physical and mental wellbeing.MethodsSeasoned yoga practitioners were recruited from the Isha Foundation. Recruitment of the comparison group was achieved using snowball sampling and were not yoga practitioners. Participants in the non-yoga group were randomized to a 3-min...