Archives of Clinical Psychiatry (São Paulo)
February 1, 2018
Rafael G. Dos Santos, Rafael Faria Sanches, Flávia de Lima Osório et al.
37 citations
Abstract Background Ayahuasca is a botanical hallucinogenic preparation traditionally used by indigenous populations of Northwestern Amazonian countries for ritual and therapeutic purposes. It is rich in β-carboline alkaloids and N,N-dimethyltryptamine (DMT). Preclinical, observational, and experimental studies suggest that ayahuasca and its alkaloids have anxiolytic and antidepressive effects....
bioRxiv (Cold Spring Harbor Laboratory)
January 25, 2018
Flávia Santos Da Silva, Erick Allan Dos Santos Silva, Geovan Menezes de Sousa et al.
4 citations
preprint
ABSTRACT The incidence of major depression in adolescents, aged between 15 to 18 years, reaches approximately 14%. Usually, this disorder presents a recurrent way, without remission of symptoms even after several pharmacological treatments, persisting through adult life. Due to the relatively low efficacy of commercially available antidepressant, new pharmacological therapies are under...
Journal of Palliative Medicine
January 22, 2018
Ira Byock
164 citations
Even with an expanding evidence base confirming safety and benefits, political, regulatory, and industry issues impose challenges to the legitimate use of psychedelics. The federal expanded access program and right-to-try laws in multiple states provide precendents for giving terminally ill patients access to medications that have not yet earned FDA approval. Given the prevalence of persistent...
Frontiers in Pharmacology
January 17, 2018
Leor Roseman, David Nutt, Robin Carhart-Harris
814 citations
Introduction: It is a basic principle of the "psychedelic" treatment model that the quality of the acute experience mediates long-term improvements in mental health. In the present paper we sought to test this using data from a clinical trial assessing psilocybin for treatment-resistant depression (TRD). In line with previous reports, we hypothesized that the occurrence and magnitude of Oceanic...
Scientific Reports
January 12, 2018
Kim P. C. Kuypers, Rafael de la Torre, Magı́ Farré et al.
12 citations
Abstract MDMA exerts its main effects via the serotonergic system and the serotonin transporter. The gene coding for this transporter determines the expression rate of the transporter. Previously it was shown that healthy individuals with the short allelic variant (‘ s -group’) of the 5-HTTLPR-polymorphism displayed more anxiety and negative mood, and had a lower transcriptional efficiency...
Psychology, Health & Medicine
January 8, 2018
Rebecca A Franklin, Michael P Butler, Jacob A Bentley
Yoga contains sub-components related to its physical postures (asana), breathing methods (pranayama), and meditation (dhyana). To test the hypothesis that specific yoga practices are associated with reduced psychological distress, 186 adults completed questionnaires assessing life stressors, symptom severity, and experience with each of these aspects of yoga. Each yoga sub-component was found...
Japanese journal of clinical oncology
January 1, 2018
Sunre Park, Mitsuhiro Sado, Daisuke Fujisawa et al.
Mindfulness-based intervention has been receiving growing attention in cancer care. This study aimed to examine feasibility and to preliminary explore effectiveness of mindfulness-based cognitive therapy (MBCT) in Japanese breast cancer patients, and to explore possible modification of the program so that it fits better with this population. Twelve participants with diagnosis of Stage I-III...
Anesthesia, essays and researches
2018
Madhuri S Kurdi, Vinod Gasti
Music therapy is a nonpharmacological modality which can provide promising results for postcesarean section recovery. The aim of this study was to compare the effects of two types of intraoperative meditation music with control group on postcesarean section pain, anxiety, nausea, vomiting, and psychological maternal wellbeing. A prospective, randomized, controlled study was conducted on 189...
Alzheimer's & Dementia
2018
Natalie L. Marchant, Thorsten Barnhofer, Olga Klimecki et al.
Subjectively experienced cognitive decline in older adults is an indicator of increased risk for dementia and is also associated with increased levels of anxiety symptoms. As anxiety is itself emerging as a risk factor for cognitive decline and dementia, the primary question of the present study is whether an 8-week mindfulness-based intervention can significantly reduce anxiety symptoms in...
Journal of integrative medicine
2018
Chandra Nanthakumar
The number of children suffering from stress and anxiety in Malaysia is on the rise. Evidence shows that mind-body therapies such as mindfulness therapy, meditation and yoga have been practiced in many other countries to reduce and/or manage the psychological effects of stress and anxiety. This review article looks at the intervention of yoga as a meditative movement practice in helping school...