PCN reports : psychiatry and clinical neurosciences
September 1, 2023
Chisato Tanaka, Kenta Wakaizumi, Akira Ninomiya et al.
3 citations
Among graduates of mindfulness-based interventions (MBIs) during the COVID-19 pandemic, those who continued regular mindfulness practice reported lower depression and higher resilience, overall health, and mental health compared to those who did not practice. The degree of perceived stress from the pandemic did not differ statistically between the groups. The effect of mindfulness practice on reducing depression was fully mediated by resilience. The findings suggest that maintaining mindfulness practice after an MBI builds resilience, which helps buffer against new stressors and may prevent depression.
Journal of Clinical Medicine
February 28, 2026
Chisato Tanaka, Yuta Shinohara, Saki Takaoka et al.
In a group of 33 adults with chronic pain who took part in an 8-week Mindfulness-Based Cognitive Therapy (MBCT) program, mood improved markedly both during individual sessions and across the entire program. Vigor increased, while depression, tension-anxiety, and confusion decreased. Participants who started with higher tension-anxiety showed the greatest gains in anger, depression, tension, and confusion. The findings suggest that MBCT can enhance emotional well-being in chronic pain patients, especially those with elevated anxiety.
JMIR cardio
February 4, 2026
Yuka Takita, Junko Morishita, Sunre Park et al.
A mindfulness-based self-management program tailored for people with pulmonary hypertension (PH) was delivered online via weekly videoconference sessions over eight weeks, combining PH self-management education with mindfulness-based cognitive therapy and supported by a mobile app and Apple Watch for symptom monitoring. Twelve participants enrolled, nine completed the program (75% retention). Quality of life and resilience significantly improved from baseline to week 8. Trends toward reduced depression and anxiety were observed, but loneliness did not change. Participants valued the online format and wearable integration, reporting increased self-awareness, better pain management through meditation, and enhanced self-compassion. The findings suggest potential benefits and warrant a future randomized trial.
Frontiers in Psychiatry
January 1, 2024
Mitsuhiro Sado, Akihiro Koreki, Akira Ninomiya et al.
For patients with panic disorder or social anxiety disorder, adding mindfulness-based cognitive therapy (MBCT) to usual care costs about JPY 13,885 more per patient over 8 weeks but improves anxiety symptoms and quality of life. The incremental cost per quality-adjusted life year (QALY) was JPY 1,566,357, well below Japan's willingness-to-pay threshold of JPY 5,000,000, giving a 77.5% probability of being cost-effective. MBCT reduced state anxiety by 10.13 points and trait anxiety by 12.00 points on the STAI. Sensitivity analyses confirmed the findings were robust.
JMIR Research Protocols
August 28, 2023
Mitsuhiro Sado, Akira Ninomiya, Maki Nagaoka et al.
A feasibility randomized controlled trial compares augmented mindfulness-based cognitive therapy (MBCT) with follow-up sessions to augmented MBCT without follow-up sessions for adults aged 20–65 with panic disorder, agoraphobia, or social anxiety disorder that has not remitted after at least 4 weeks of usual treatment. The 8-week MBCT program includes a 10-month follow-up period. Primary outcomes are inclusion rate, dropout rate, attendance rate, and clinical measures at 8 weeks and 5, 8, and 12 months. Recruitment began in January 2020 and 43 participants were enrolled by January 2021; data collection is expected to finish by May 2022. The study is limited by mixed intervention delivery modes and lack of a pharmacotherapy-alone arm.
Frontiers in Psychology
September 4, 2021
Teppei Kosugi, Akira Ninomiya, Maki Nagaoka et al.
Eight weeks of mindfulness-based cognitive therapy, followed by two monthly classes, improves both cognitive and affective aspects of subjective well-being and eudaimonic well-being in healthy community residents with initially low life satisfaction. Cognitive well-being and mindfulness skills improved significantly by 8 weeks, and these gains continued through the 16-week follow-up. Positive affect and eudaimonic well-being showed significant improvement only at 16 weeks. The order of improvement was cognitive, then positive affective, then eudaimonic well-being.