Physician burnout is widespread in health care systems, with harmful consequences on physicians, patients, and health care organizations. Mindfulness training (MT) has proven effective in reducing burnout; however, its time-consuming requirements often pose challenges for physicians who are already struggling with their busy schedules. This study aimed to design a short and pragmatic digital MT...
Perinatal mental health problems, such as anxiety, stress, and depression, warrant particularly close monitoring and intervention, but they are often unaddressed in both obstetric and psychiatric clinics, with limited accessibility and treatment resources. Mobile health interventions may provide an effective and more accessible solution for addressing perinatal mental health. Development and...
Abstract Rationale Psychedelic-assisted therapy is increasingly applied within mental health treatment. Objectives This study focused on factors moderating changes in the acute and long-term effects of an individual psilocybin-assisted program on depression, anxiety, PTSD and personality structures by including demographic factors, subjective experience and degree of mystical type experiences...
medRxivJanuary 5, 2025Vinitha Ganesan, Lauren A. Fowler, Sahil Bajaj et al.1 citation
preprint
Abstract Effective interventions are needed to address increasing mental health challenges that affect wellbeing. Sudarshan Kriya Yoga (SKY), a breath-based meditation, has previously shown to improve mental health. We conducted a pilot randomized controlled trial (RCT) in healthy individuals, to evaluate the feasibility of SKY intervention with an eight-week followup for studying its immediate...
Objective: Anxious students during their studies have low academic self-efficacy and face challenges in school adjustment. Therefore, the present study was conducted with the aim of determine the effect of mindfulness-based education on academic self-efficacy and school adjustment in anxious female students. Methodology: This research was a quasi-experimental with a pre-test and post-test...
Cancer remains one of the leading causes of mortality worldwide and has a profound impact on an individual's psychological well-being. Individuals diagnosed with breast cancer often experience anxiety, depression, and reduced quality of life (QoL) due to the physical and emotional burden of the disease. Mindfulness-based interventions have emerged as effective strategies to alleviate...
Background: The Altered States of Consciousness Scale (3/5D-ASC or 11-ASC) is widely used to assess non-ordinary states of consciousness, particularly for psychedelic research. However, its original dimensional model (3D-ASC within 5D-ASC) and later 11-subscale structure (11-ASC) have a hierarchically incompatible higher/lower-order structure. Although the 11-ASC offers superior model fit, the...
Ketamine2025Jose Eduardo Guimaraes Pereira, Carlos Darcy Alves Bersot, Thiago Ramos Grigio et al.1 citation
Neuropathic pain (NP) is a frequently undertreated component of chronic pain, posing challenges due to its complexity. This has led to interest in N-methyl-D-aspartate receptor (NMDAR) antagonists like ketamine. NP is linked to maladaptive processes, such as NMDAR-related windup and sensitization. While results from ketamine trials on chronic NP have been inconsistent, perioperative use has...
2025Henrique Tofoli Vieira Machado, Geovana Mendes de Seixas, L. Silva et al.
Introduction: In recent years, psilocybin has been explored as an alternative therapy for neurological and psychiatric disorders, such as depression, anxiety, post-traumatic stress disorder (PTSD), and substance dependence. Studies suggest that when administered under professional supervision, psilocybin can offer relief for patients with treatment-resistant disorders. Objective: The aim of...
The well-being of medical students is affected by high stress levels. The relevance of a mindfulness mediation app (Med@Med) specifically produced to help medical students at a Portuguese medical school cope with stress was evaluated. The app, consisting of 21 short meditations, was totally developed in Portuguese to fulfill with the needs of some of the students. The motivations to use the...