Background. Post-Traumatic Stress Disorder (PTSD) is an important public health challenge typically treated with trauma-focused psychotherapy and Selective Serotonin Reuptake Inhibitors (SSRIs). However, high rates of residual symptoms associated with these standard treatments have led to a renewed interest in psychedelic-assisted therapies. Aim. This review attempts to examine emerging...
JMIR Mental HealthJuly 15, 2026Xichun Wu, Jackelyn De Alwis, Zenan Dou et al.
Background: Mobile mindfulness interventions have shown promise for reducing anxiety and depressive symptoms, but sustaining engagement remains a persistent challenge. Many digital programs still rely on formal practice that requires dedicated time, which may be difficult to integrate into daily life. Objective: This randomized controlled trial evaluated Habitual Mindfulness Practice (HMP), a...
La regulación emocional constituye una dimensión relevante en el deporte juvenil, debido a la presencia de ansiedad, estrés, presión competitiva y demandas psicológicas asociadas al entrenamiento y la competencia. En este contexto, las aplicaciones móviles y las intervenciones digitales basadas en mindfulness se han propuesto como recursos complementarios para apoyar el bienestar psicológico y...
Dissociative psychoactive substances (such as ketamine and PCP) present a challenge to standard models of altered states of consciousness. Unlike classical hallucinogens which enrich or distort conscious content, dissociatives induce a peculiar fragility in the construction of one’s world-model – a breakdown of the high-level coherence that ordinarily binds perception, selfhood, and meaning....
In acute trials of intravenous and intranasal ketamine/esketamine, the rapid anti-suicidal effect appears to be at least partly independent of the overall antidepressant response. That question has, to our knowledge, never been examined in a real-world esketamine cohort followed for six months, nor in a sample enriched for comorbid borderline personality disorder (BPD), a population excluded...
Jurnal Sistem Informasi GaluhJuly 11, 2026Bacilius Agung Suburdjati, Lisda Sukoco, Claire Gretchen Tjandraprawira et al.
This study aims to analyze the effect of an intervention (meditation sessions) on subjects’ anxiety levels, which were objectively measured through Heart Rate Variability (HRV) using the MAX30102 sensor. Anxiety has become an increasingly dominant mental health issue in modern society, creating the need for non-pharmacological and measurable intervention methods. The study employed a One Group...
Objective Students in higher education (HE) increasingly experience challenging concerns from stress to anxiety and depression. Mindfulness-based interventions (MBIs) became a popular strategy to help students cope with these. This systematic review aimed to evaluate the efficacy, scalability and sustainability of various MBIs implemented in HE to identify strengths, limitations and possible...
This review synthesizes work on fear of negative evaluation (FNE), thought suppression, and the possible moderating role of mindfulness. FNE is a social-cognitive vulnerability marked by worry over others' judgment, rejection, or devaluation. Suppression, in turn, refers to deliberate efforts to exclude unwanted cognitive content from awareness. Recent work has tied evaluative fear to...
Stress exposure during periods of neurodevelopment is an established risk factor for the onset of stress-related mental illnesses in adulthood, which have differences in presentation and treatment response depending on an individual’s sex, and are difficult to treat due to a lack of complete biological understanding. A more holistic biological perspective of the adult brain after stress...
Anxiety and stress-related disorders affect over 280 million individuals worldwide and remain inadequately treated by current pharmacotherapies, which are often limited in efficacy and tolerability. Ketamine produces rapid therapeutic effects in mood and anxiety disorders, but its clinical use is constrained by dissociative side effects and abuse liability. Ketamine metabolites, particularly (2...