Chronic Stress
August 12, 2020
Alan K. Davis, Lynnette A. Averill, Nathan D. Sepeda et al.
83 citations
Background U.S. Special Operations Forces Veterans are at increased risk for a variety of mental health problems and cognitive impairment associated with military service. Current treatments are lacking in effectiveness and adherence. Therefore, this study examined psychedelic treatment with ibogaine and 5-methoxy-N,N-dimethyltryptamine for trauma-related psychological and cognitive impairment...
Journal of Pharmaceutical and Biomedical Analysis
July 21, 2020
Izumi Morita, Hiroyuki Oyama, Yuki Kiguchi et al.
17 citations
Development of rapid and reliable immunochemical methods for monitoring psilocybin (4-phosphoryloxy-N,N-dimethyltryptamine; Pyb) and psilocin (dephosphorylated metabolite; Psi), the psychoactive compounds contained within hallucinogenic mushrooms (magic mushrooms), is desirable in order to identify these mushrooms and regulate their illicit use. Because no antibody was publicly available for...
Plants
July 9, 2020
Beatriz Werneck Lopes Santos, Regina Célia de Oliveira, Júlia Sonsin‐oliveira et al.
32 citations
Ayahuasca is a psychoactive infusion with a large pharmacological application normally prepared with Banisteriopsis caapi, which contains the monoamine oxidase inhibitors β-carbolines, and Psichotria virids, which contains the serotonin receptor agonist N,N dimethyltryptamine (DMT). The objectives of this study were to investigate the chemical profile of B. caapi and of ayahuasca collected in...
Acta Crystallographica. Section E, Crystallographic Communications
July 3, 2020
Andrew R Chadeayne, Duyen N. K. Pham, James A. Golen et al.
The structures of the hydrofumarate salts of two N,N-dimethyltryptamine (DMT) derivatives, the synthetic psychedelics N-ethyl-N-propyltryptamine (EPT) and N-allyl-N-methyltryptamine (MALT), are reported.
Brazilian Journal of Psychiatry
July 3, 2020
Simon Ruffell, Nige Netzband, Catherine Bird et al.
43 citations
Ayahuasca is a South American psychoactive plant brew used as traditional medicine in spiritual and in cultural rituals. This is a review of the current understanding about the pharmacological mechanisms that may be interacting in ayahuasca. Searches were performed using PubMed, PsycINFO, and Web of Science databases and 16 papers were selected. As hypothesized, the primary narrative in...
Journal of Ethnopharmacology
June 12, 2020
Albert Katchborian‐neto, Wanderleya T Santos, Karen J Nicácio et al.
62 citations
Ayahuasca is a tea produced through decoction of Amazonian plants. It has been used for centuries by indigenous people of South America. The beverage is considered to be an ethnomedicine, and it is traditionally used for the treatment of a wide range of diseases, including neurological illness. Besides, some scientific evidence suggests it may be applicable to Parkinson's disease (PD)...
Journal of Psychoactive Drugs
June 12, 2020
Jason B. Luoma, Christina Chwyl, Geoff J. Bathje et al.
206 citations
After a two-decade hiatus in which research on psychedelics was essentially halted, placebo-controlled clinical trials of psychedelic-assisted therapy for mental health conditions have begun to be published. We identified nine randomized, placebo-controlled clinical trials of psychedelic-assisted therapy published since 1994. Studies examined psilocybin, LSD (lysergic acid diethylamide),...
The Journal of Antibiotics
May 12, 2020
David E. Nichols
184 citations
Psilocybin (4-phosphoryloxy-N,N-dimethyltryptamine) is an indole-based secondary metabolite produced by numerous species of mushrooms. South American Aztec Indians referred to them as teonanacatl, meaning "god's flesh," and they were used in religious and healing rituals. Spanish missionaries in the 1500s attempted to destroy all records and evidence of the use of these mushrooms. Nevertheless,...
Psychiatria Polska
April 30, 2020
Aleksandra Barabasz-Gembczyk, Krzysztof Kucia
4 citations
Ayahuaska, zwana również „lianą duszy”, „pnączem duszy” to rytualny psychodelik podawany tradycyjnie w formie wywaru roślinnego, od stuleci stosowany przez rdzenną ludność Ameryki Południowej, a w ostatnich 25 latach również w krajach Europy, Azji, Afryki, Australii, w Kanadzie i Stanach Zjednoczonych Ameryki Północnej. Jej aktywność biologiczna wynika z zawartości N,N- dimetrylotryptaminy...
Forensic Science International
April 17, 2020
Sarah Eller, Gabriela Ramos Borges, Daniela Souza Ossanes et al.
13 citations
IntroductionAyahuasca is a beverage composed by a mixture of herbs which contain the compound N,N-dimethyltriptamine (DMT) and the β-carbolines. Although its use is legalized in Brazil only for religious and spiritual ceremonies, there is a growing black market specialized in the distribution of these compounds in form of herbal material through internet and mail. The purpose of this work was...