Indole alkaloids from Ervatamia orientalis . I. Isolation of alkaloids and structural identification of two dimers
Australian Journal of Chemistry August 1, 1975 DOI: 10.1071/ch9751813 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Phytochemical isolation and structural elucidation Peer reviewed |
|---|---|
| Population | Ethanol extracts of the plant Ervatamia orientalis |
| Citations | 35 |
| Key points | Ethanol extracts of Ervatamia orientalis contained nine known alkaloids and yielded five previously unreported compounds: two new voacamine-group dimers (16-demethoxycarbonyldihydrovoacamine and 16-demethoxycarbonyl-20'-epi-dihydrovoacamine) and three novel 2-acylindoles (ervatamine, 20-epiervatamine, and 19-dehydroervatamine). The new dimeric compounds were identified by physical and chemical methods. |
Abstract
Ethanol extracts of Ervatamia orientalis have yielded the following known alkaloids: ibogaine, iboxygaine, voacristine, vobasine, dregamine, tabernaemontanine, apparicine, voacamine and 16- demethoxycarbonylvoacamine. In addition, two new dimeric alkaloids of the voacamine group and the novel 2-acylindoles ervatamine, 20- epiervatamine and 19-dehydroervatamine have been isolated from the extracts. The two new dimeric compounds have been identified by physical and chemical methods as 16-demethoxycarbonyldihydrovoacamine and 16-demethoxycarbonyl-20?-epi-dihydrovoacamine.