Obovamine, a New Indole Alkaloid fromStemmadenia obovata
Alberto Madinaveitia, Matı́as Reina, Gabriel de la Fuente, Antonio G. González, Emir Valencia
Journal of Natural Products 1996 DOI: 10.1021/np960049b (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Phytochemical isolation and structure elucidation study Peer reviewed |
|---|---|
| Population | Stem bark of the Panamanian plant Stemmadenia obovata |
| Citations | 14 |
| Key points | The stem bark of Stemmadenia obovata contains a previously unreported ibogaine-type alkaloid, obovamine, whose structure the authors determined from spectral data and chemical correlations. Ten known alkaloids were also isolated, and voacangine was reported as the main alkaloid constituent. |
Abstract
The stem bark of the Panamanian plant Stemmademia obovata has afforded a new ibogaine-type alkaloid, obovamine ( 1 ), whose structure was determined by a combination of spectral interpretation and chemical correlations. Ten known alkaloids, coronaridine, coronaridine hydroxyindolenine, voacangine, voacangine hydroxyindolenine, (19 S )-heyneanine, (19 S )-heyneanine hydroxyindolenine, (19 S )-voacristine, (19 S )-voacristine hydroxyindolenine, ajmalicine, and ajmalicinine, were also isolated. Voacangine was the main alkaloid constituent.