Mindfulness‐based stress reduction for mental health in youth: a cluster randomized controlled trial
Sunita Vohra, Salima Punja, Erica Ms Sibinga, Lola T. Baydala, Erik Wikman, Anthony Singhal, Florin Dolcos, K. Jessica van Vliet
Child and Adolescent Mental Health October 15, 2018 DOI: 10.1111/camh.12302 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized cluster-controlled trial Peer reviewed |
|---|---|
| Sample size | 85 |
| Population | Adolescents aged 12-18 residing in CASA House, a voluntary residential treatment program |
| Interventions | Mindfulness-based stress reduction (MBSR) usual care |
| Duration | Eight MBSR sessions of 2 hr/week |
| Measures | Behavior Assessment System for Children, Second Edition (BASC-2) |
| Topics | Meditation |
| Citations | 35 |
| Registration | NCT01307943 |
| Key findings | MBSR plus usual care produced significantly better teacher-rated internalizing problems and adaptive skills on the BASC-2 than usual care alone, with no significant differences on other outcomes. A post hoc analysis found a significantly shorter time to discharge in the MBSR arm. The authors conclude MBSR is effective for improved coping with internalizing problems and adaptive emotional skills in this sample. |
Abstract
Background: Mental illness is among the most common causes of morbidity, mortality, and disability in childhood. Mindfulness-based stress reduction (MBSR) has shown significant benefit in mental health; however, evidence of its effectiveness in youth is limited. The objective of this study was to compare the efficacy of MBSR plus usual care versus usual care alone for reducing mental health symptoms in youth.
Methods: A two-arm, mixed methods, randomized cluster-controlled trial of 12-18 year olds who were residents of CASA House, a voluntary residential treatment program for adolescents, between January 2011 and March 2013 (clinicaltrials.gov, NCT01307943).
Interventions: Treatment terms were randomized to usual care, or MBSR plus usual care, which included eight MBSR sessions of 2 hr/week.
Outcomes: The primary outcome was impact on emotions and behavior at the end of the program, using the Behavior Assessment System for Children, Second Edition (BASC-2). Secondary outcomes included perceived stress levels, mindfulness, and emotional regulation.
Results: A total of 85 participants were randomized to either the MBSR arm (n = 45) or control arm (n = 40). Significant differences in favor of MBSR were found on Teacher ratings of the Internalizing Problems (p = .038) and Adaptive Skills subscales (p = .022) on the BASC-2. No significant differences were found on other outcomes. A post hoc analysis found that the MBSR arm had a significantly shorter time to discharge (p = .02).
Conclusion: The results of this study indicate that MBSR is effective for improved coping with internalizing problems and adaptive emotional skills in our sample. Future studies should focus on larger, longer-term studies in youth.
Comparable studies
Other randomized controlled trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment | 2003 | Randomized controlled trial | n = 41 |
| Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients | 2000 | Randomized controlled trial | n = 145 |
| Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults | 2008 | Randomized controlled trial | n = 139 |
| Short-term meditation training improves attention and self-regulation Undergraduate Chinese students | 2007 | Randomized controlled trial | n = 40 |
| Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients | 2004 | Randomized controlled trial | n = 73 |
Citations in the library
Cited by 6
- Mindfulness in Mental Health and Psychiatric Disorders of Children and Adolescents: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Pediatric Reports May 14, 2025
- The effects of mindfulness‐based interventions on emotion regulation/dysregulation in people with mental health conditions: A systematic review and meta‐analysis JCPP Advances February 12, 2026
- Context Always Matters: A Grassroots Model for a Mindfulness Program in Schools Contemporary School Psychology June 16, 2026
- Outcomes of Mindfulness Therapy for Adolescents with Mental Health Issues: A Scoping Review March 1, 2026
- Peacefull: A French mindfulness-based intervention for adolescents with chronic pain a feasibility study. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie November 1, 2022
and 1 more in the library
Cites 17
- Mindfulness training as a clinical intervention: A conceptual and empirical review. Clinical Psychology Science and Practice 2003
- A randomized controlled trial of mindfulness meditation versus relaxation training: Effects on distress, positive states of mind, rumination, and distraction Annals of Behavioral Medicine February 1, 2007
- A Randomized, Wait-List Controlled Clinical Trial: The Effect of a Mindfulness Meditation-Based Stress Reduction Program on Mood and Symptoms of Stress in Cancer Outpatients Psychosomatic Medicine September 1, 2000
- Assessing mindfulness in children and adolescents: Development and validation of the Child and Adolescent Mindfulness Measure (CAMM). Psychological Assessment April 11, 2011
- Mindfulness-based stress reduction for the treatment of adolescent psychiatric outpatients: A randomized clinical trial. Journal of Consulting and Clinical Psychology 2009
and 12 more in the library