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Mindfulness in severe and persistent mental illness: a systematic review.

Angela Potes, Gabriel Souza, Katerina Nikolitch, Romeo Penheiro, Yara Moussa, Eric Jarvis, Karl Looper, Soham Rej

International Journal of Psychiatry in Clinical Practice November 2018 DOI: 10.1080/13651501.2018.1433857 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review Randomized Qualitative Peer reviewed
Population Individuals with severe and persistent mental illness (SPMI)
Intervention Mindfulness-based interventions
Topics Meditation
Keywords Bipolar Psychosis Severe mental illness
Key findings The review indicates that mindfulness is feasible for people with SPMI and is associated with clinical improvements in psychotic symptoms, depression symptoms, cognition, mindfulness, and psycho-social and vocational outcomes. The authors conclude that effects on psychotic symptoms remain uncertain and call for larger, methodologically rigorous studies with thorough assessments and more representative SPMI populations.

Abstract

This systematic review summarises the current state of research on mindfulness in SPMI, given the pressing need to provide alternative, scalable and cost-effective treatment modalities for patients with severe and persistent mental illness (SPMI). Articles included mindfulness-based interventions for SPMI. Excluded articles included qualitative studies, acceptance and compassion therapies, case reports and reviews. Studies were identified by searching the databases Medline, Embase and PsycINFO. Six randomised controlled trials, seven prospective studies and one retrospective study were identified. Clinical improvements were observed on psychotic symptoms, and on improvements of depression symptoms, cognition, mindfulness, psycho-social and vocational factors. Findings suggest that mindfulness is feasible for individuals with SPMI, and displays potential benefits in outcomes aside from psychotic symptoms. The effects of mindfulness in psychotic symptoms needs further investigation in larger definitive studies using methodological rigor and thorough assessments of other psychiatric populations who are also representative of SPMI.

Comparable studies

Other systematic reviews and meta-analyses on meditation, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis Healthy subjects 2009 Systematic review and meta-analysis
The psychological effects of meditation: A meta-analysis. Nonclinical groups of adult meditators 2012 Meta-analysis n = 163
Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse Adults with recurrent depression in full or partial remission 2016 Meta-analysis of individual patient data from randomized controlled trials n = 1,258
Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials 2011 Systematic review

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