Mindfulness- and Acceptance-based Interventions for Psychosis: A Systematic Review and Meta-analysis.
Holger Cramer, Romy Lauche, Heidemarie Haller, Jost Langhorst, Gustav J Dobos
Global Advances in Health and Medicine 2016 DOI: 10.7453/gahmj.2015.083 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Systematic review Randomized Peer reviewed |
|---|---|
| Sample size | 434 |
| Population | Patients with psychosis |
| Intervention | Acceptance-based interventions |
| Topics | Meditation |
| Keywords | Meta-analysis Systematic review Psychosis Acceptance |
| Key findings | The review reports moderate evidence that mindfulness- and acceptance-based interventions improve total and positive psychotic symptoms, hospitalization rates and duration, and mindfulness in the short term, with long-term effects on total psychotic symptoms and hospitalization duration. It found no evidence of effects on negative symptoms, affect, or acceptance, and no serious adverse events. The authors conclude these interventions can be recommended as an additional treatment for psychosis. |
Abstract
Background: Mindfulness- and acceptance-based interventions are increasingly studied as a potential treatment for a variety of mental conditions.
Objective: To assess the effects of mindfulness- and acceptance-based interventions on psychotic symptoms and hospitalization in patients with psychosis.
Methods: MEDLINE/PubMed, Embase, the Cochrane Library, and PsycINFO were screened from inception through April 2015. Randomized controlled trials (RCTs) were analyzed when they assessed psychotic symptoms or hospitalization in patients with psychosis; affect, acceptance, mindfulness, and safety were defined as secondary outcomes.
Results: Eight RCTs with a total of 434 patients comparing mindfulness-based (4 RCTs) or acceptance-based interventions (4 RCTs) to treatment as usual or attention control were included. Six RCTs had low risk of bias. Moderate evidence was found for short-term effects on total psychotic symptoms, positive symptoms, hospitalization rates, duration of hospitalization, and mindfulness and for long-term effects on total psychotic symptoms and duration of hospitalization. No evidence was found for effects on negative symptoms, affect, or acceptance. No serious adverse events were reported.
Conclusion: Mindfulness- and acceptance-based interventions can be recommended as an additional treatment for patients with psychosis.
Comparable studies
Other systematic reviews and meta-analyses on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations | 2014 | Meta-analysis | n = 3,515 |
| Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis Healthy subjects | 2009 | Systematic review and meta-analysis | |
| The psychological effects of meditation: A meta-analysis. Nonclinical groups of adult meditators | 2012 | Meta-analysis | n = 163 |
| Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse Adults with recurrent depression in full or partial remission | 2016 | Meta-analysis of individual patient data from randomized controlled trials | n = 1,258 |
| Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials | 2011 | Systematic review |
Citations in the library
Cited by 15
- Mindfulness-based interventions: an overall review British Medical Bulletin April 21, 2021
- Real-time fMRI neurofeedback reduces auditory hallucinations and modulates resting state connectivity of involved brain regions: Part 2: Default mode network -preliminary evidence Psychiatry Research January 14, 2020
- Mindfulness for psychosis: Current evidence, unanswered questions and future directions Psychology and Psychotherapy Theory Research and Practice June 30, 2023
- Mindfulness Meditation Training Reduces Gaming Cravings by Reshaping the Functional Connectivity Between the Default Mode Network and Executive Control-Related Brain Regions. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging August 1, 2024
- What and who? Mindfulness in the mental health setting BJPsych Bulletin December 1, 2016
and 10 more in the library
Cites 12
- Assessment of Mindfulness by Self-Report Assessment September 1, 2004
- Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials Acta Psychiatrica Scandinavica April 28, 2011
- Mindfulness-based cognitive therapy for depression. Industrial Psychiatry Journal October 29, 2024
- Mindfulness-Based Stress Reduction for Breast Cancer—A Systematic Review and Meta-Analysis Current Oncology October 1, 2012
- Mindfulness-based stress reduction for low back pain. A systematic review. BMC Complementary and Alternative Medicine September 25, 2012
and 7 more in the library