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Who experiences depressive symptoms following mindfulness-based stress reduction and why?

Patricia Lynn Dobkin, Qinyi Zhao, Kaveh Monshat

International Journal of Whole Person Care January 27, 2017 DOI: 10.26443/ijwpc.v4i1.123 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational cohort Peer reviewed
Sample size 126
Population Patients with various medical and psychological conditions
Intervention Mindfulness-Based Stress Reduction (MBSR)
Topics Meditation
Key findings Depression screening rates fell from 49% to 27% after MBSR. Patients who remained depressed scored lower on sense of coherence, used more emotional coping and less palliative and distraction coping, and improved less on stress. Low pre-program meaningfulness predicted more post-program depressive symptoms; the authors conclude these patients could not reappraise their lives to become stress resilient.

Abstract

Background: A small percentage of patients screen positive for depression following a mindfulness-based program. We identified patient characteristics associated with this outcome in order to understand this phenomenon.Methods: Depressive symptoms, stress, mindfulness, coping with illness and sense of coherence were measured in 126 patients with various medical and psychological conditions pre- and post- Mindfulness-Based Stress Reduction (MBSR).

Results: Fewer patients (27% vs. 49%) screened positive for depression post-MBSR. Both pre- and post-MBSR patients who were depressive following MBSR scored lower on meaningfulness, comprehensibility, and manageability (sense of coherence), higher on emotional coping and lower on palliative and distraction coping. Smaller positive changes (e.g. stress) occurred in these patients as well. Viewing life as less meaningful pre-MBSR predicted more symptoms of depression post-MBSR.Conclusions: Patients who suffered depressive symptoms following the program were unable to reappraise their lives in such a way as to become stress resilient.

Comparable studies

Other observational and cohort studies on meditation, most cited first.

Study Year Design Participants
Using Self-Report Assessment Methods to Explore Facets of Mindfulness Undergraduate students 2006 Observational cohort
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders Patients with generalized anxiety disorder or panic disorder with or without agoraphobia 1992 Observational cohort n = 22
Meditation experience is associated with increased cortical thickness Participants with extensive Insight meditation experience and matched controls 2005 Observational cohort n = 20
Meditation experience is associated with differences in default mode network activity and connectivity Experienced meditators and matched meditation-naive controls 2011 Observational cohort
Long-term meditators self-induce high-amplitude gamma synchrony during mental practice Long-term Buddhist practitioners and controls 2004 Observational cohort

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