Effect of Mindfulness-Based Stress Reduction on Anxiety, Depression and Stress in Women With Multiple Sclerosis.
Bentolhoda Kolahkaj, Fatemeh Zargar
Nursing and midwifery studies December 2015 DOI: 10.17795/nmsjournal29655 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Peer reviewed |
|---|---|
| Sample size | 40 |
| Population | Women with multiple sclerosis in Ahvaz, Iran |
| Duration | 8-week intervention with 1-month follow-up |
| Measures | Depression, Anxiety and Stress Scale (DASS-21) |
| Topics | Anxiety Depression Meditation |
| Keywords | Multiple sclerosis Stress |
| Key findings | Eight sessions of mindfulness-based stress reduction significantly reduced mean depression, anxiety, and stress scores in women with multiple sclerosis compared with usual care. Depression fell from 8.35 to 4.80 after the intervention and 4.45 at one-month follow-up; anxiety from 8.90 to 4.70 and 4.55; and stress from 8.80 to 4.80 and 4.70. The authors suggest MBSR is useful for these psychological problems in MS patients. |
Abstract
Studies suggest that mindfulness-based interventions can improve anxiety, depression and stress in patients with multiple sclerosis (MS). However, no study investigated the effectiveness of this method in patients with a combination of problems such as depression, anxiety and stress simultaneously. However, comorbidities of depression and anxiety in MS are prevalent. This study aimed to assess the effects of mindfulness-based stress reduction (MBRS) on anxiety, depression and stress in women with multiple sclerosis. This randomized controlled clinical trial was performed in 2013 in Ahvaz MS Society. Forty eight patients were selected by convenient sampling and randomly assigned in experimental and control groups. The patients in the two groups filled out depression, anxiety and stress scale (DASS-21) at initiation of study, 8 weeks later and 1 month after the end of intervention. The experimental group received 8 sessions of MBRS, while the control group treated as usual. Finally, data of 40 patients analyzed using t-test, chi square and repeated measures analysis of variance. In the MBSR group, the mean depression, anxiety and stress were reduced significantly (P < 0.001). The mean depression score was 8.35 ± 1.78 before the intervention and reduced to 4.80 ± 0.83 and 4.45 ± 0.60 after the intervention and follow-up (P < 0.001). Also the mean anxiety score was 8.90 ± 1.97 before the intervention, which was significantly reduced to 4.70 ± 1.38 and 4.55 ± 0.99 after the intervention and follow-up (P < 0.001). The mean stress score was also 8.80 ± 2.35 before treatment and 4.80 ± 1.67 and 4.70 ± 1.34 after the intervention and follow-up (P < 0.001). This study showed that MBSR training can reduce mean depression, anxiety and stress scores in patients with MS. These findings suggest that MBSR is useful for psychological problems such as depression, anxiety and stress in patients with MS.
Comparable studies
Other randomized controlled trials on anxiety, most cited first.
Citations in the library
Cited by 19
- Impact of mindfulness-based stress reduction for people with multiple sclerosis at 8 weeks and 12 months: A randomized clinical trial Multiple Sclerosis Journal July 9, 2018
- Into the Moment: Does Mindfulness Affect Biological Pathways in Multiple Sclerosis? Frontiers in Behavioral Neuroscience May 22, 2018
- Effectiveness of a Combined Mindfulness-Based Cognitive Therapy and Mindfulness-Based Stress Reduction Intervention on Depression Symptoms and Quality of Life in a Group of Iranian Veterans with Posttraumatic Stress Disorder Iranian Journal of Psychiatry and Behavioral Sciences September 15, 2018
- The Effect of Mindfulness-Based Stress Reduction (MBSR) on Emotional Flexibility and Ambivalence Over Emotional Expression in Divorced Women: A Pilot Randomized Controlled Trial. The Journal of Nervous and Mental Disease April 1, 2023
- A Pilot Study of Telehealth Mindfulness-Based Cognitive Therapy for Depression in Parkinson's Disease. Journal of geriatric psychiatry and neurology March 2023
and 14 more in the library
Cites 9
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- Self-Focused Attention and Mechanisms of Change in Mindfulness-Based Treatment Cognitive Behaviour Therapy 2009
- Mindfulness-based Stress Reduction (MBSR) Reduces Anxiety, Depression, and Suicidal Ideation in Veterans Medical Care November 13, 2014
- Sustained Impact of MBSR on Stress, Well-Being, and Daily Spiritual Experiences for 1 Year in Academic Health Care Employees The Journal of Alternative and Complementary Medicine October 1, 2011
and 4 more in the library