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Effectiveness of a Combined Mindfulness-Based Cognitive Therapy and Mindfulness-Based Stress Reduction Intervention on Depression Symptoms and Quality of Life in a Group of Iranian Veterans with Posttraumatic Stress Disorder

Abdollah Omidi, Sajedeh Hamidian

Iranian Journal of Psychiatry and Behavioral Sciences September 15, 2018 DOI: 10.5812/ijpbs.55945 (opens in new tab)

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Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial Peer reviewed
Sample size 62
Population Combat veterans with comorbid PTSD and depression
Interventions Mindfulness-based stress reduction (MBSR) Mindfulness-based cognitive therapy (MBCT)
Topics Depression Meditation PTSD
Citations 6
Key findings The combined MBSR and MBCT intervention significantly reduced depression scores in the treatment group compared with the control group (P < 0.05). The abstract states that total and subscale PTSD scores were also analyzed, but the reported text is truncated before those results appear.

Abstract

Background: Comorbidity of anxiety and mood disorders is rather common, making the treatment of each disorder more difficult. Posttraumatic stress disorder (PTSD) is one of the anxiety disorders with a high degree of association with depression; PTSD-depression comorbidity can significantly affect the quality of life of the ones affected. Hence, using the best way to deal with each of these disorders is highly recommended.

Objectives: The current study aimed at evaluating the effectiveness of a combined treatment of mindfulness-based stress reduction (MBSR) and mindfulness-based cognitive therapy (MBCT) on PTSD and comorbid depression in combat veterans.

Methods: Among patients referring to Kashan Veterans Counseling Center, 62 patients diagnosed with comorbid PTSD and depression according to diagnostic and statistical manual of mental disorders-fourth edition-text revision (DSM-IV-TR) were selected, and randomly assigned into the two groups of case and control. The study was conducted in 2012.

Results: Statistical analysis showed that after the intervention, the depression scores of the case group significantly decreased, while the similar trend was not observed in the control group (P < 0.05). Furthermore, the total score and the scores of

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The safety and efficacy of {+/-}3,4-methylenedioxymethamphetamine-assisted psychotherapy in subjects with chronic, treatment-resistant posttraumatic stress disorder: the first randomized controlled pilot study. Patients with chronic post-traumatic stress disorder refractory to both psychotherapy... 2010 Randomized controlled trial n = 20
Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder Patients with chronic PTSD related to a range of trauma exposures 2014 Randomized controlled trial n = 41
3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for post-traumatic stress disorder in military veterans, firefighters, and police officers: a randomised, double-blind, dose-response, phase 2 clinical trial. Military veterans and first responders aged 18 or older with chronic PTSD lasting 6... 2018 Randomized, double-blind, dose-response, phase 2 clinical trial n = 26
A randomized, controlled pilot study of MDMA (±3,4-Methylenedioxymethamphetamine)-assisted psychotherapy for treatment of resistant, chronic Post-Traumatic Stress Disorder (PTSD) Patients with treatment-resistant PTSD 2012 Randomized controlled trial n = 12

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Depression Meditation PTSD Anxiety