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Efficacy of Internet-Delivered Mindfulness for Improving Depression in Caregivers of People With Spinal Cord Injuries and Chronic Neuropathic Pain: A Randomized Controlled Feasibility Trial.

Jasmine Heath Hearn, Imogen Cotter, Katherine Anne Finlay

Archives of Physical Medicine and Rehabilitation January 2019 DOI: 10.1016/j.apmr.2018.08.182 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled feasibility study Peer reviewed
Sample size 55
Population Spouses or family caregivers (older than 18 years, with Internet access) of people with spinal cord injury and chronic neuropathic pain
Interventions Web-based mindfulness training Psychoeducational materials
Dose 10 minutes of mindfulness practices, twice per day, 6 days per week, totaling 960 minutes
Duration 8-week intervention, 3-month follow-up
Topics Anxiety Meditation Depression
Keywords Education Quality of life Rehabilitation Telemedicine
Key points Internet-delivered mindfulness training reduced depression severity and anxiety more than psychoeducation among caregivers of people with spinal cord injury and chronic neuropathic pain, with benefits maintained at 3 months. The authors conclude the approach is viable and suggest future combined education and mindfulness programs involving both patient and caregiver.

Abstract

To explore the feasibility and efficacy of web-based mindfulness training for carers of people with spinal cord injury (SCI). Randomized controlled feasibility study with 3-month follow-up. Community setting. Spouses or family caregivers (N=55) of people with SCI and chronic neuropathic pain were recruited via the direct care team and advertisements. Participants were older than 18 years (no upper age limit), with Internet access for the duration of the study. Participants were randomly allocated to an 8-week online mindfulness training intervention (n=28), or to receive 8 weeks of psychoeducational materials on SCI and chronic pain (n=27). An established web-based, mindfulness training course was delivered over 8 weeks. Participants completed 10 minutes of mindfulness practices, twice per day, 6 days per week, totaling 960 minutes. The control group received a weekly e-mail with psychoeducational materials (based on the established elements) on SCI and pain for 8 weeks. Depression severity. Mindfulness reduced depression severity more than psychoeducation at T2 (mean difference= -.891; 95% confidence interval,-1.48 to -.30) and T3 (mean difference=-1.96; 95% confidence interval, -2.94 to -.97). Mindfulness training also reduced anxiety at T2 (mean difference=-.888; 95% confidence interval, -1.40 to -.38) and T3 (mean difference=-2.44; 95% confidence interval, -3.20 to -1.69). Results indicate that Internet-delivered mindfulness training offers unique benefits and is viable for caregivers of people with SCI and chronic neuropathic pain. Further work should explore the feasibility of combined education and mindfulness training incorporating both patient and caregiver, for optimum benefit.

Comparable studies

Other randomized controlled trials on depression, most cited first.

Study Year Design Participants
A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression Subjects with DSM-IV major depression (treatment resistant) 2006 Randomized, placebo-controlled, double-blind crossover study n = 18
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Cancer patients with life-threatening diagnoses and symptoms of depression and/or anxiety 2016 Randomized controlled trial n = 51
Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial Patients with cancer-related anxiety and depression 2016 Double-blind, placebo-controlled, crossover trial n = 29
Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients 2004 Randomized controlled trial n = 73

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